{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T20:40:03Z","timestamp":1756327203639,"version":"3.44.0"},"reference-count":13,"publisher":"BMJ","issue":"5","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,4,20]]},"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:p>Pityriasis rubra pilaris (PRP) is a rare dermatological condition which may present with ocular manifestations. We report a case of recurrent cicatricial ectropion (CE) with topical beta-blocker use in the rare dermatological condition PRP. The patient underwent release of scar tissue, lateral tarsal strip and full-thickness supraclavicular skin graft for CE following immunosuppression with methotrexate for 3\u2009months. Postoperatively, CE recurred, with skin graft shrinkage and resumption of periocular disease activity, 8\u2009weeks following the introduction of topical timolol. The patient was referred for further immunosuppression and substitution of timolol before consideration for further surgery. PRP has a variety of potential ocular complications. Surgery has a high risk of recurrence and should be performed when the overall disease is quiescent and drugs, which could trigger reactivation, have been discontinued and\/or substituted. Skin grafts should be oversized to off-set shrinkage.<\/jats:p>","DOI":"10.1136\/bcr-2023-256445","type":"journal-article","created":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T22:35:14Z","timestamp":1716935714000},"page":"e256445","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Ophthalmic complication of pityriasis rubra pilaris"],"prefix":"10.1136","volume":"17","author":[{"given":"Malik","family":"Moledina","sequence":"first","affiliation":[{"name":"Southend University Hospital NHS Foundation Trust, Southend-on-Sea, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Davison","sequence":"additional","affiliation":[{"name":"Barking Havering and Redbridge University Hospitals NHS Trust, Romford, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adeela","family":"Malik","sequence":"additional","affiliation":[{"name":"Southend University Hospital NHS 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