{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T10:20:54Z","timestamp":1758709254293,"version":"3.44.0"},"reference-count":41,"publisher":"BMJ","issue":"8","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,7,25]]},"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:p>A man in his 50s presented with sudden onset expressive aphasia and right-sided facial droop after experiencing coryzal symptoms and malaise for 7\u2009days prior to admission. A brain MRI showed a rapidly progressive mass effect across both hemispheres and cerebrospinal fluid analysis revealed neutrophil predominance with raised protein levels. Acute disseminated encephalomyelitis was provisionally diagnosed, and high-dose methylprednisone was initiated.<\/jats:p>\n               <jats:p>On admission to the high dependency unit, the patient tested positive for COVID-19 and was treated with appropriate therapeutic agents for severe COVID-19. A subsequent brain biopsy confirmed a demyelinating process, strongly indicating a diagnosis of acute haemorrhagic leucoencephalitis when correlated with the presence of severe oedema on imaging. Nine sessions of plasma exchange were provided over 18 days.<\/jats:p>\n               <jats:p>At the time of writing, the patient has made an excellent recovery. We urge clinicians to consider this diagnosis and these treatment options for an otherwise devastating condition.<\/jats:p>","DOI":"10.1136\/bcr-2023-256640","type":"journal-article","created":{"date-parts":[[2024,8,9]],"date-time":"2024-08-09T00:36:46Z","timestamp":1723163806000},"page":"e256640","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Recovery from acute haemorrhagic leucoencephalitis secondary to COVID-19"],"prefix":"10.1136","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-1473-018X","authenticated-orcid":false,"given":"Nicholas","family":"Bunting","sequence":"first","affiliation":[{"name":"Coffs Harbour Base Hospital, Coffs Harbour, New South Wales, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Martynoga","sequence":"additional","affiliation":[{"name":"Waikato Hospital, Hamilton, Waikato, New 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