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Obsessive-compulsive behaviours were first observed on discharge from the hospital and became worse over time. Compulsive behaviours were considered in light of a neuropsychological examination, and a diagnosis of OCD was attained. Sertraline was prescribed and effectively reduced the severity of OCD symptoms. Given the challenges comorbid conditions can pose to neurorehabilitation, a better understanding of patterns in OCD symptoms and brain lesions among reported cases will help guide the diagnosis of OCD among individuals with severe TBI.<\/jats:p>","DOI":"10.1136\/bcr-2023-256834","type":"journal-article","created":{"date-parts":[[2024,1,10]],"date-time":"2024-01-10T03:45:19Z","timestamp":1704858319000},"page":"e256834","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Obsessive-compulsive disorder following severe traumatic brain injury"],"prefix":"10.1136","volume":"17","author":[{"given":"Alison Janelle","family":"Wilson","sequence":"first","affiliation":[{"name":"Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Regan","family":"King","sequence":"additional","affiliation":[{"name":"Pediatrics, University of Calgary, Cumming School of Medicine, Calgary, Alberta, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2704-0438","authenticated-orcid":false,"given":"Chantel","family":"Debert","sequence":"additional","affiliation":[{"name":"Clinical Neurosciences, University of Calgary, Cumming School of Medicine, Calgary, Alberta, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,1,9]]},"reference":[{"key":"2025082712123268000_17.1.e256834.1","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1080\/13554794.2012.690423","article-title":"Diagnosis and treatment of an obsessive\u2013compulsive disorder following traumatic brain injury: A single case and review of the literature","volume":"19","author":"Hofer","year":"2013","journal-title":"Neurocase"},{"key":"2025082712123268000_17.1.e256834.2","doi-asserted-by":"crossref","unstructured":"American Psychiatric Association . 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