{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:05:23Z","timestamp":1756339523237,"version":"3.44.0"},"reference-count":11,"publisher":"BMJ","issue":"2","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,2,5]]},"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:p>We present a case of a male neonate who experienced a 13.5%\u2009weight loss at 96 hours of life, despite receiving adequate calorie intake and exhibiting no feeding difficulties. The pregnancy was uneventful, and maternal serological investigation was normal. A routine ultrasound at 34 weeks of gestational age revealed late oligohydramnios. The neonate was delivered at 35 weeks of gestational age by forceps, weighing 2600\u2009g. Physical examination disclosed bilateral cryptorchidism. Laboratory studies unveiled acute kidney injury (AKI) with hyperkalaemia. Renal ultrasound revealed bilateral hydronephrosis and renal dysplasia with pyelocalyceal dilatation. Despite early recognition and treatment, the newborn developed chronic kidney disease (CKD). AKI is an important and under-recognised cause of significant neonatal weight loss.<\/jats:p>\n               <jats:p>This case underscores the significance of considering AKI as a potential and under-recognised cause of neonatal weight loss. It emphasises the importance of maintaining a high clinical suspicion for early AKI diagnosis to mitigate the risk of progression to CKD.<\/jats:p>","DOI":"10.1136\/bcr-2023-256947","type":"journal-article","created":{"date-parts":[[2024,2,14]],"date-time":"2024-02-14T12:35:19Z","timestamp":1707914119000},"page":"e256947","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Acute renal failure as a key to significant neonatal weight loss"],"prefix":"10.1136","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9017-9558","authenticated-orcid":false,"given":"Joana","family":"Moscoso","sequence":"first","affiliation":[{"name":"Pediatrics, Hospital de S\u00e3o Francisco Xavier, Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margarida","family":"Ser\u00f4dio","sequence":"additional","affiliation":[{"name":"Pediatrics, Hospital de S\u00e3o Francisco Xavier, Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Rita","family":"Prior","sequence":"additional","affiliation":[{"name":"Pediatrics, Hospital de S\u00e3o Francisco Xavier, Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,2,14]]},"reference":[{"key":"2025082709085589000_17.2.e256947.1","first-page":"295","article-title":"Failure to thrive: a practical guide","volume":"94","author":"Homan","year":"2016","journal-title":"Am Fam Physician"},{"key":"2025082709085589000_17.2.e256947.2","unstructured":"Eichenwald E , Hansen A , Martin C , et al . Cloherty and stark\u2019s Manual of neonatal care. Lippincott Williams & Wilkins, 2016: 367\u2013400."},{"key":"2025082709085589000_17.2.e256947.3","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1007\/s40746-018-0138-8","article-title":"Acute kidney injury in term neonates","volume":"4","author":"Kupferman","year":"2018","journal-title":"Curr Treat Options Peds"},{"key":"2025082709085589000_17.2.e256947.4","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.siny.2016.12.001","article-title":"Acute kidney injury in the fetus and neonate","volume":"22","author":"Nada","year":"2017","journal-title":"Seminars Fetal Neonatal Med"},{"key":"2025082709085589000_17.2.e256947.5","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-015-3298-9"},{"key":"2025082709085589000_17.2.e256947.6","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2014-3819"},{"key":"2025082709085589000_17.2.e256947.7","unstructured":"Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group . KDIGO Clinical Practice Guideline for Acute Kidney Injury. Kidney Int Suppl;2:1\u2013138."},{"key":"2025082709085589000_17.2.e256947.8","first-page":"1","article-title":"Criteria for determining disability in infants and children: failure to thrive","volume":"72","author":"Perrin","year":"2003","journal-title":"Evid Rep Technol Assess (Summary)"},{"key":"2025082709085589000_17.2.e256947.9","unstructured":"Gomella TL , Eyal FG , Bany-Mohammed F . Gomella\u2019s Neonatology Management, Procedures, on-Call Problems, Diseases and Drugs. New York: Mc Graw Hill Lange, 2020."},{"key":"2025082709085589000_17.2.e256947.10","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/j.jogn.2019.09.004","article-title":"Systematic review of expected weight changes after birth for full-term, breastfed newborns","volume":"48","author":"DiTomasso","year":"2019","journal-title":"J Obstet Gynecol Neonatal Nurs"},{"key":"2025082709085589000_17.2.e256947.11","first-page":"829","article-title":"Failure to thrive: an update","volume":"83","author":"Cole","year":"2011","journal-title":"Am Fam Physician"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2023-256947","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T16:09:04Z","timestamp":1756310944000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2023-256947"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2]]},"references-count":11,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2024,2,14]]},"published-print":{"date-parts":[[2024,2]]}},"alternative-id":["10.1136\/bcr-2023-256947"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2023-256947","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2024,2]]}}}