{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T14:10:05Z","timestamp":1756303805042,"version":"3.44.0"},"reference-count":10,"publisher":"BMJ","issue":"12","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2023,12,17]]},"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:p>Often termed as \u2018vanishing mystery\u2019 epidemiologically, endomyocardial fibrosis (EMF) continues to be the the most common cause of restrictive cardiomyopathy in Africa and some parts of the Indian subcontinent, where it is considered a significant public health problem. On the other hand, in developed countries, it is considered a rare phenomenon. This entity is considered incurable due to lack of targeted therapies, even after 75 years since its discovery. The authors describe here a case of an Indian male, in his early 30s who presented with complaints of dyspnoea on minimal daily activities, swelling of both legs and abdominal fullness for 3\u2009months. The clinical features were suggestive of isolated right heart failure. He was diagnosed with EMF on echocardiography and the findings were confirmed on cardiac MRI. The patient has progressed to develop biventricular dysfunction and is being managed symptomatically with diuretics due to unavailability of targeted treatment options at present.<\/jats:p>","DOI":"10.1136\/bcr-2023-257017","type":"journal-article","created":{"date-parts":[[2023,12,28]],"date-time":"2023-12-28T12:10:51Z","timestamp":1703765451000},"page":"e257017","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Endomyocardial fibrosis: a tragic conundrum or a mere negligence?"],"prefix":"10.1136","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3298-6217","authenticated-orcid":false,"given":"Bhavik Sandip","family":"Shah","sequence":"first","affiliation":[{"name":"Cardiology, KEM Hospital and Seth G S Medical College, Mumbai, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charan","family":"Lanjewar","sequence":"additional","affiliation":[{"name":"Cardiology, KEM Hospital and Seth G S Medical College, Mumbai, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2023,12,28]]},"reference":[{"key":"2025082706474637000_16.12.e257017.1","first-page":"729","article-title":"Tropical endomyocardial fibrosis in India: a vanishing disease","volume":"136","author":"Vijayaraghavan","year":"2012","journal-title":"Indian J Med Res"},{"doi-asserted-by":"publisher","key":"2025082706474637000_16.12.e257017.2","DOI":"10.1136\/hrt.2007.136101"},{"key":"2025082706474637000_16.12.e257017.3","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/j.jaccas.2020.02.020","article-title":"Tropical endomyocardial fibrosis","volume":"2","author":"Sutter","year":"2020","journal-title":"JACC Case Rep"},{"key":"2025082706474637000_16.12.e257017.4","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0000097","article-title":"Endomyocardial fibrosis: still a mystery after 60 years","volume":"2","author":"Bukhman","year":"2008","journal-title":"PLoS Negl Trop Dis"},{"key":"2025082706474637000_16.12.e257017.5","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.case.2021.06.002","article-title":"Multimodality imaging in endomyocardial fibrosis: an unusual etiology of heart failure","volume":"5","author":"Velandia-Carrillo","year":"2021","journal-title":"CASE (Phila)"},{"doi-asserted-by":"publisher","key":"2025082706474637000_16.12.e257017.6","DOI":"10.1056\/NEJMoa0708629"},{"doi-asserted-by":"publisher","key":"2025082706474637000_16.12.e257017.7","DOI":"10.1161\/CIRCIMAGING.110.950675"},{"doi-asserted-by":"publisher","key":"2025082706474637000_16.12.e257017.8","DOI":"10.1161\/CIRCULATIONAHA.115.021178"},{"doi-asserted-by":"publisher","key":"2025082706474637000_16.12.e257017.9","DOI":"10.1016\/S1010-7940(99)00027-5"},{"doi-asserted-by":"publisher","key":"2025082706474637000_16.12.e257017.10","DOI":"10.1056\/NEJMoa025217"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2023-257017","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T13:47:53Z","timestamp":1756302473000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2023-257017"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":10,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2023,12,28]]},"published-print":{"date-parts":[[2023,12]]}},"alternative-id":["10.1136\/bcr-2023-257017"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2023-257017","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2023,12]]}}}