{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T04:04:42Z","timestamp":1777435482550,"version":"3.51.4"},"reference-count":9,"publisher":"BMJ","issue":"11","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2023,10,2]]},"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:p>In this case report, we present a late preterm growth-restricted neonate who developed signs of feeding intolerance on the second day of life, which progressed to frank peritonitis with perforation by the end of the second week of life. As necrotising enterocolitis was considered the most likely diagnosis, a glove drain was placed in the flanks. The neonate did not improve, and surgical exploration was done after medical stabilisation. On exploration, the neonate was found to have appendicular perforation and an appendicectomy was performed. During surgery, the rest of the gut was noted to be healthy. Histopathological examination of the appendix showed transmural inflammation, focal infarction and perforation. The postoperative period was uneventful, and the neonate showed rapid improvement and reached full enteral feeding in the next 5\u2009days. Antibiotic therapy promptly resolved bacterial peritonitis, and the neonate was discharged successfully.<\/jats:p>","DOI":"10.1136\/bcr-2023-257097","type":"journal-article","created":{"date-parts":[[2023,11,9]],"date-time":"2023-11-09T10:31:12Z","timestamp":1699525872000},"page":"e257097","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Neonatal perforated appendicitis: a presentation of necrotising enterocolitis?"],"prefix":"10.1136","volume":"16","author":[{"given":"Prathit","family":"Naik","sequence":"first","affiliation":[{"name":"Kasturba Medical College, Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajendra Prasad","family":"Anne","sequence":"additional","affiliation":[{"name":"Kasturba Medical College, Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheila Samanta","family":"Mathai","sequence":"additional","affiliation":[{"name":"Kasturba Medical College, Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6408-0447","authenticated-orcid":false,"given":"Nitin","family":"Pai","sequence":"additional","affiliation":[{"name":"Kasturba Medical College, Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2023,11,9]]},"reference":[{"key":"2025082702470413000_16.11.e257097.1","unstructured":"Ginglen JG , Butki N . Necrotizing Enterocolitis. In: StatPearls. Treasure Island (FL): StatPearls Publishing, 2023. 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