{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:06:17Z","timestamp":1756339577069,"version":"3.44.0"},"reference-count":22,"publisher":"BMJ","issue":"8","license":[{"start":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T00:00:00Z","timestamp":1723593600000},"content-version":"unspecified","delay-in-days":13,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,7,1]]},"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:p>A woman in her 20s with no medical history was diagnosed with bulky stage II classic Hodgkin\u2019s lymphoma after an 8-week history of shortness of breath, cough and lethargy. A regimen of doxorubicin (Adriamycin), bleomycin, vinblastine and dacarbazine (ABVD) was commenced with six cycles planned. During the first cycle, the patient was profoundly hypertensive. She then suffered two self-terminating tonic-clonic seizures.<\/jats:p>\n               <jats:p>Examination and investigations diagnosed posterior reversible encephalopathy syndrome (PRES), which resolved completely in 11 days with strict blood pressure control and withholding chemotherapy. Treatment was further complicated by anthracycline-induced cardiomyopathy, requiring a switch in regimen to gemcitabine BVD.<\/jats:p>\n               <jats:p>The patient made a full recovery from neurology and cardiology perspectives and completed six cycles of chemotherapy, achieving a complete metabolic response by the tumour. We illustrate the case, describe differential diagnoses and management of PRES, its association with chemotherapy and the successful chemotherapy rechallenge.<\/jats:p>","DOI":"10.1136\/bcr-2023-257523","type":"journal-article","created":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T21:25:15Z","timestamp":1723670715000},"page":"e257523","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Posterior reversible encephalopathy syndrome (PRES) in classic Hodgkin\u2019s lymphoma, complicated by anthracycline-induced cardiomyopathy"],"prefix":"10.1136","volume":"17","author":[{"given":"Rose","family":"Hall","sequence":"first","affiliation":[{"name":"Royal Marsden Hospital NHS Trust, Chelsea, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bambang","family":"Atmaja","sequence":"additional","affiliation":[{"name":"Royal Marsden Hospital NHS Trust, Chelsea, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bhupinder","family":"Sharma","sequence":"additional","affiliation":[{"name":"Royal Marsden Hospital NHS Trust, Chelsea, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Cunningham","sequence":"additional","affiliation":[{"name":"Royal Marsden Hospital NHS Trust, Chelsea, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,8,14]]},"reference":[{"key":"2025082711183729000_17.8.e257523.1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199602223340803"},{"key":"2025082711183729000_17.8.e257523.2","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdq382"},{"key":"2025082711183729000_17.8.e257523.3","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(12)70135-7"},{"key":"2025082711183729000_17.8.e257523.4","doi-asserted-by":"crossref","DOI":"10.1093\/omcr\/omx011","article-title":"Posterior reversible encephalopathy syndrome(PRES)","volume":"2017","author":"Sudulagunta","year":"2017","journal-title":"Oxf Med Case Rep"},{"key":"2025082711183729000_17.8.e257523.5","doi-asserted-by":"publisher","DOI":"10.1136\/practneurol-2021-003194"},{"key":"2025082711183729000_17.8.e257523.6","doi-asserted-by":"crossref","DOI":"10.3174\/ajnr.A1285","article-title":"Catheter angiography, MR angiography, and MR perfusion in posterior reversible encephalopathy syndrome","volume":"30","author":"Schwartz","year":"2009","journal-title":"AJNR Am J Neuroradiol"},{"key":"2025082711183729000_17.8.e257523.7","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2020.00071","article-title":"Posterior reversible encephalopathy syndrome: clinical features and outcome","volume":"11","author":"Hinduja","year":"2020","journal-title":"Front Neurol"},{"key":"2025082711183729000_17.8.e257523.8","doi-asserted-by":"crossref","first-page":"70","DOI":"10.17116\/jnevro20161167170-77","article-title":"Posterior reversible encephalopathy syndrome due to hypocalcemia: a description of a case and an analysis of a pathogenic role of electrolyte disturbances","volume":"116","author":"Dobrynina","year":"2016","journal-title":"Zh Nevrol Psikhiatr Im S S Korsakova"},{"key":"2025082711183729000_17.8.e257523.9","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1634\/theoncologist.2014-0149","article-title":"Posterior reversible encephalopathy syndrome in patients with cancer","volume":"20","author":"Singer","year":"2015","journal-title":"Oncol"},{"key":"2025082711183729000_17.8.e257523.10","doi-asserted-by":"crossref","DOI":"10.1007\/s11916-020-00932-1","article-title":"Posterior reversible encephalopathy syndrome","volume":"25","author":"Gewirtz","year":"2021","journal-title":"Curr Pain Headache Rep"},{"key":"2025082711183729000_17.8.e257523.11","doi-asserted-by":"publisher","DOI":"10.3747\/pdi.2012.00152"},{"key":"2025082711183729000_17.8.e257523.12","doi-asserted-by":"crossref","unstructured":"Moritani T , Ekholm S , Westesson PLA . 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