{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T10:07:16Z","timestamp":1767866836027,"version":"3.49.0"},"reference-count":16,"publisher":"BMJ","issue":"8","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,8,13]]},"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:p>Angioedema is a rare but potentially fatal complication of angiotensin-converting enzyme inhibitor (ACEi) treatment. This class of drugs is widely used in the treatment of hypertension, cardiac failure and other common conditions.<\/jats:p>\n               <jats:p>This case report discusses a male patient in his 60s who presented with acute swelling of the right side of his tongue, an unusual manifestation of angioedema, which typically involves bilateral swelling of orofacial structures.<\/jats:p>\n               <jats:p>Accurate and early identification of this complication affords the opportunity for early, potentially life-saving intervention during the acute episode and also cessation of the treatment, reducing the risk of recurrence in the future.<\/jats:p>\n               <jats:p>This case is one of only a few reported in English language medical literature and the first from Africa, suggesting either rarity or under-reporting. The case contributes to the understanding of ACEi-induced angioedema, particularly in Africa where hypertension is prevalent and ACEi is commonly used.<\/jats:p>","DOI":"10.1136\/bcr-2023-257959","type":"journal-article","created":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T12:05:34Z","timestamp":1725019534000},"page":"e257959","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Unilateral tongue swelling: an unusual presentation of angiotensin-converting enzyme inhibitor-related angioedema"],"prefix":"10.1136","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-9730-621X","authenticated-orcid":false,"given":"Julian Robert Paul","family":"Eloff","sequence":"first","affiliation":[{"name":"Emergency Medicine, Karl Bremer Hospital, Cape Town, Western Cape, South 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