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This is a case of metastatic rectal squamous cell carcinoma presenting in a 22-week pregnant, female patient in her early 30s. The patient was treated with 5-fluorouracil and cisplatin and delivered a healthy male child born via uncomplicated vaginal delivery at 35 weeks. This article demonstrates that despite the rare nature of this cancer, in the already rare context of pregnancy, effective and safe treatment is possible with a multidisciplinary team.<\/jats:p>","DOI":"10.1136\/bcr-2023-257984","type":"journal-article","created":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T22:40:18Z","timestamp":1708468818000},"page":"e257984","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Treatment of metastatic rectal squamous cell carcinoma in a pregnant patient"],"prefix":"10.1136","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0491-6641","authenticated-orcid":false,"given":"Nathan S","family":"Kau","sequence":"first","affiliation":[{"name":"Department of Medicine, Division of Medical Oncology, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeannie 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