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This report presents a unique case of a woman in her 80s with a <jats:italic>TET2<\/jats:italic>-mutant UPS metastatic to the lung and brain.<\/jats:p>","DOI":"10.1136\/bcr-2023-258139","type":"journal-article","created":{"date-parts":[[2024,6,18]],"date-time":"2024-06-18T22:35:14Z","timestamp":1718750114000},"page":"e258139","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["<i>TET2<\/i>-mutant undifferentiated pleomorphic sarcoma metastatic to lung and brain"],"prefix":"10.1136","volume":"17","author":[{"given":"Sophia","family":"Wix","sequence":"first","affiliation":[{"name":"Texas Christian University Anne Burnett Marion School of Medicine, Fort Worth, Texas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Winston","family":"Scambler","sequence":"additional","affiliation":[{"name":"Texas Christian University Anne Burnett Marion School of Medicine, Fort Worth, Texas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinh","family":"Trang","sequence":"additional","affiliation":[{"name":"Texas Oncology, Fort Worth, Texas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rehan A","family":"Malik","sequence":"additional","affiliation":[{"name":"Texas Christian University Anne Burnett Marion School of Medicine, Fort Worth, Texas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2024,6,18]]},"reference":[{"key":"2025082723170450000_17.6.e258139.1","unstructured":"Fletcher CDM , World Health Organization . 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Brain metastases in patients with soft-tissue Sarcomas: management and survival-A SEER population-based cohort study. 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