{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T05:56:04Z","timestamp":1778824564476,"version":"3.51.4"},"reference-count":20,"publisher":"BMJ","issue":"12","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2023,11,15]]},"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:p>Enteropathy-associated T cell lymphoma (EATL) is an aggressive subtype of non-Hodgkin\u2019s lymphoma often associated with coeliac disease (CD). We describe a previously healthy man in his 50\u2009s who presented with a history of abdominal pain, failure to thrive and significant weight loss over a 3-month period. Investigations revealed a positive coeliac serology, diffuse duodenal atrophy with multiple duodenal and jejunal ulcers on endoscopy and mesenteric lymphadenopathy on CT imaging. Duodenal tissue biopsy confirmed a diagnosis of EATL Stage IVB. Chemotherapy with cyclophosphamide, doxorubicin, vincristine and prednisone regimen was initiated. This case highlights the need for greater awareness and consideration of EATL in individuals with worsening malabsorption and abdominal pain, irrespective of coeliac history.<\/jats:p>","DOI":"10.1136\/bcr-2023-258265","type":"journal-article","created":{"date-parts":[[2023,12,23]],"date-time":"2023-12-23T09:55:19Z","timestamp":1703325319000},"page":"e258265","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Advanced enteropathy-associated T cell lymphoma (EATL) presenting with severe malabsorption and concomitantly diagnosed coeliac disease (CD)"],"prefix":"10.1136","volume":"16","author":[{"given":"Anjali","family":"Rajagopal","sequence":"first","affiliation":[{"name":"Department of Medicine, AI & Innovation, Mayo Clinic, Rochester, Minnesota, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carrie A","family":"Thompson","sequence":"additional","affiliation":[{"name":"Division of Hematology, Mayo Clinic Rochester, Rochester, Minnesota, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allison K","family":"Chorzempa","sequence":"additional","affiliation":[{"name":"Division of Hospital Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander J","family":"Ryu","sequence":"additional","affiliation":[{"name":"Division of Hospital Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2023,12,23]]},"reference":[{"key":"2025082802253748000_16.12.e258265.1","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1007\/s11899-021-00634-4","article-title":"Enteropathy-associated T cell lymphoma","volume":"16","author":"Al Somali","year":"2021","journal-title":"Curr Hematol Malig Rep"},{"key":"2025082802253748000_16.12.e258265.2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-01-643569"},{"key":"2025082802253748000_16.12.e258265.3","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-02-335216"},{"key":"2025082802253748000_16.12.e258265.4","doi-asserted-by":"crossref","unstructured":"Delabie JMA . Enteropathy-associated T-cell lymphoma [Encyclopedia of Pathology]. In: Molina TJ , ed. Hematopathology. Cham: Springer International Publishing, 2020: 137\u201342.","DOI":"10.1007\/978-3-319-95309-0_1970"},{"key":"2025082802253748000_16.12.e258265.5","doi-asserted-by":"publisher","DOI":"10.1007\/s11899-018-0459-5"},{"key":"2025082802253748000_16.12.e258265.6","doi-asserted-by":"publisher","DOI":"10.1080\/00365520802240222"},{"key":"2025082802253748000_16.12.e258265.7","doi-asserted-by":"crossref","DOI":"10.1007\/s11894-020-0756-8","article-title":"Refractory celiac disease","volume":"22","author":"Hujoel","year":"2020","journal-title":"Curr Gastroenterol Rep"},{"key":"2025082802253748000_16.12.e258265.8","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2012.12.001"},{"key":"2025082802253748000_16.12.e258265.9","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2020-322935"},{"key":"2025082802253748000_16.12.e258265.10","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-10-385559"},{"key":"2025082802253748000_16.12.e258265.11","doi-asserted-by":"crossref","DOI":"10.1182\/blood-2021-153709","article-title":"The Eatl-001 trial: results of a phase 2 study of Brentuximab Vedotin and CHP followed by consolidation with high-dose therapy - Autologous stem-cell transplantation (HDT-ASCT) in the frontline treatment of patients with enteropathy-associated T-cell lymphoma","volume":"138","author":"Sibon","year":"2021","journal-title":"Blood"},{"key":"2025082802253748000_16.12.e258265.12","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-07-231324"},{"key":"2025082802253748000_16.12.e258265.13","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1159\/000369542","article-title":"Enteropathy-associated T-cell lymphoma: improving treatment strategies","volume":"33","author":"Nijeboer","year":"2015","journal-title":"Dig Dis"},{"key":"2025082802253748000_16.12.e258265.14","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2017-08-802470"},{"key":"2025082802253748000_16.12.e258265.15","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2018-317371"},{"key":"2025082802253748000_16.12.e258265.16","doi-asserted-by":"crossref","first-page":"7584","DOI":"10.3748\/wjg.v26.i47.7584","article-title":"Multiple cerebral lesions in a patient with refractory celiac disease: a case report","volume":"26","author":"Horvath","year":"2020","journal-title":"World J Gastroenterol"},{"key":"2025082802253748000_16.12.e258265.17","doi-asserted-by":"crossref","first-page":"5781","DOI":"10.12998\/wjcc.v8.i22.5781","article-title":"Early colon cancer with enteropathy-associated T-cell lymphoma involving the whole gastrointestinal tract: a case report","volume":"8","author":"Zhang","year":"2020","journal-title":"World J Clin Cases"},{"key":"2025082802253748000_16.12.e258265.18","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1080\/20009666.2018.1483693","article-title":"An unexpected deterrent in diagnosing refractory celiac disease and enteropathy-associated T-cell lymphoma: a gluten-free diet","volume":"8","author":"Hussain","year":"2018","journal-title":"J Community Hosp Intern Med Perspect"},{"key":"2025082802253748000_16.12.e258265.19","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1080\/25785826.2019.1673031","article-title":"A case of celiac disease with type I enteropathy-associated T-cell lymphoma in a Japanese male patient","volume":"42","author":"Hiraga","year":"2019","journal-title":"Immunol Med"},{"key":"2025082802253748000_16.12.e258265.20","first-page":"FD10","article-title":"Enteropathy associated T cell lymphoma \u2013 A case report of an uncommon extranodal T cell lymphoma","volume":"8","author":"V","year":"2014","journal-title":"J Clin Diagn Res"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2023-258265","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:25:44Z","timestamp":1756373144000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2023-258265"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":20,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2023,12,23]]},"published-print":{"date-parts":[[2023,12]]}},"alternative-id":["10.1136\/bcr-2023-258265"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2023-258265","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12]]}}}