{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:04:22Z","timestamp":1756425862028,"version":"3.44.0"},"reference-count":12,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2023,12,24]]},"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p>Breast necrotising soft tissue infections (NSTIs) are rare surgical emergencies with limited cases described in the literature. Here, we discuss a unique case of a woman in her 70s who presented with newly diagnosed diabetes and a neglected right breast cancer associated with breast erythema, skin necrosis, crepitus on examination and breast soft tissue gas seen on CT requiring emergent total mastectomy with partial pectoralis muscle excision. Pathology revealed a 15\u2009cm invasive mucinous adenocarcinoma and necrotising polymicrobial cellulitis with a large abscess cavity. She recovered from her surgery with strict glycaemic control and a 10-day course of antibiotics. Multidisciplinary tumour board recommended adjuvant anastrozole, abemaciclib and postmastectomy radiation to complete her oncological treatment. Although exceedingly rare, it is important that clinicians be aware of, promptly recognise and properly treat NSTIs of the breast, as correct care can be life-saving from both infection and malignancy.<\/jats:p>","DOI":"10.1136\/bcr-2023-258609","type":"journal-article","created":{"date-parts":[[2024,1,12]],"date-time":"2024-01-12T13:06:25Z","timestamp":1705064785000},"page":"e258609","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Necrotising cellulitis of the breast associated with a fungating mucinous adenocarcinoma"],"prefix":"10.1136","volume":"17","author":[{"given":"Marnie","family":"Abeshouse","sequence":"first","affiliation":[{"name":"Breast Surgery, The Mount Sinai Hospital, New York, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martina","family":"Lopez-May","sequence":"additional","affiliation":[{"name":"Breast Surgery, The Mount Sinai Hospital, New York, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie","family":"Bernik","sequence":"additional","affiliation":[{"name":"Breast Surgery, The Mount Sinai Hospital, New York, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6236-6089","authenticated-orcid":false,"given":"Tara","family":"Balija","sequence":"additional","affiliation":[{"name":"Breast Surgery, The Mount Sinai Hospital, New York, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,1,12]]},"reference":[{"key":"2025082804261570000_17.1.e258609.1","article-title":"Necrotizing fasciitis of the breast: case report with literature review","volume":"2018","author":"ALShareef","year":"2018","journal-title":"Case Rep Surg"},{"key":"2025082804261570000_17.1.e258609.2","article-title":"Necrotizing fasciitis of the breast requiring a life-saving mastectomy: a case report and 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