{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T20:55:56Z","timestamp":1761598556703,"version":"3.44.0"},"reference-count":19,"publisher":"BMJ","issue":"4","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,4,20]]},"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:p>We present a case of Takayasu\u2019s arteritis in a woman in her 30s, who exhibited visual symptoms and ophthalmic manifestations of the disease, specifically Takayasu\u2019s retinopathy stage 4, in both eyes. Despite severe narrowing of all branches of the aortic arch and compromised perfusion in both upper limbs, she had no history of intermittent claudication. Doppler study and CT angiography revealed diffuse circumferential wall thickening of bilateral common carotid, subclavian and axillary arteries. Treatment involved retinal laser photocoagulation and immune suppression. This case underscores that advanced Takayasu\u2019s retinopathy can be an initial presentation of Takayasu\u2019s arteritis even in a state of severely compromised peripheral limb circulation.<\/jats:p>","DOI":"10.1136\/bcr-2023-258688","type":"journal-article","created":{"date-parts":[[2024,4,29]],"date-time":"2024-04-29T13:50:49Z","timestamp":1714398649000},"page":"e258688","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Bilateral Takayasu\u2019s retinopathy as the initial presentation of Takayasu\u2019s arteritis"],"prefix":"10.1136","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9439-2268","authenticated-orcid":false,"given":"Vikas","family":"Ambiya","sequence":"first","affiliation":[{"name":"Armed Forces Medical College, Pune, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7883-5118","authenticated-orcid":false,"given":"Abhishek","family":"Kumar","sequence":"additional","affiliation":[{"name":"Army Hospital Research and Referral, New Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vijay K","family":"Sharma","sequence":"additional","affiliation":[{"name":"Armed Forces Medical College, Pune, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashok","family":"Sharma","sequence":"additional","affiliation":[{"name":"Armed Forces Medical College, Pune, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,4,29]]},"reference":[{"key":"2025082800314951000_17.4.e258688.1","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-198503000-00002"},{"key":"2025082800314951000_17.4.e258688.2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(77)80178-6"},{"key":"2025082800314951000_17.4.e258688.3","doi-asserted-by":"crossref","DOI":"10.1186\/1752-1947-7-179","article-title":"Takayasu arteritis presenting with massive cerebral ischemic infarction in a 35-year-old woman: a case report","volume":"7","author":"Gao","year":"2013","journal-title":"J Med Case Rep"},{"key":"2025082800314951000_17.4.e258688.4","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.57.1.27"},{"key":"2025082800314951000_17.4.e258688.5","doi-asserted-by":"crossref","first-page":"148","DOI":"10.4103\/0301-4738.60090","article-title":"A case of unusual presentation of Takayasu\u2019s arteritis","volume":"58","author":"Das","year":"2010","journal-title":"Indian J Ophthalmol"},{"key":"2025082800314951000_17.4.e258688.6","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0b013e3181fe540b"},{"key":"2025082800314951000_17.4.e258688.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2012.05.010"},{"key":"2025082800314951000_17.4.e258688.8","first-page":"499","article-title":"Kawasaki disease and Takayasu arteritis - chicken or egg","volume":"18","author":"Seko","year":"2019","journal-title":"Autoimmun Rev"},{"key":"2025082800314951000_17.4.e258688.9","doi-asserted-by":"publisher","DOI":"10.1097\/01.md.0000180042.42156.d1"},{"key":"2025082800314951000_17.4.e258688.10","doi-asserted-by":"publisher","DOI":"10.1002\/art.37715"},{"key":"2025082800314951000_17.4.e258688.11","doi-asserted-by":"publisher","DOI":"10.1080\/03009740510026526"},{"key":"2025082800314951000_17.4.e258688.12","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1097\/BOR.0000000000000343","article-title":"Takayasu arteritis: an update","volume":"29","author":"Seyahi","year":"2017","journal-title":"Curr Opin Rheumatol"},{"key":"2025082800314951000_17.4.e258688.13","first-page":"S9","article-title":"Takayasu arteritis: clinical features in 110 Mexican Mestizo patients and cardiovascular impact on survival and prognosis","volume":"26","author":"Soto","year":"2008","journal-title":"Clin Exp Rheumatol"},{"key":"2025082800314951000_17.4.e258688.14","doi-asserted-by":"crossref","unstructured":"Uyama M , Asayama K . Retinal vascular changes in Takayasu\u2019s disease (Pulseless disease), occurrence and evolution of the lesion. In: International symposium on fluorescein angiography ghent 28 March\u20141 April 1976. Netherlands: Springer, 1976: 549\u201354.","DOI":"10.1007\/978-94-010-1573-8_78"},{"key":"2025082800314951000_17.4.e258688.15","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-120-11-199406010-00004"},{"key":"2025082800314951000_17.4.e258688.16","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-12-0131"},{"key":"2025082800314951000_17.4.e258688.17","doi-asserted-by":"crossref","DOI":"10.1186\/s13256-017-1330-3","article-title":"Bilateral ocular ischemia-induced blindness as a presenting manifestation of Takayasu arteritis: a case report","volume":"11","author":"Pallangyo","year":"2017","journal-title":"J Med Case Rep"},{"key":"2025082800314951000_17.4.e258688.18","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.2147\/OPTH.S12331","article-title":"Hypoperfusive and hypertensive ocular manifestations in Takayasu arteritis","volume":"4","author":"Peter","year":"2010","journal-title":"Clin Ophthalmol"},{"key":"2025082800314951000_17.4.e258688.19","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajoc.2020.100706","article-title":"A case of anti-VEGF therapy application in Takayasu arteries with retinopathy","volume":"19","author":"Gong","year":"2020","journal-title":"Am J Ophthalmol Case Rep"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2023-258688","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T07:32:01Z","timestamp":1756366321000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2023-258688"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":19,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2024,4,29]]},"published-print":{"date-parts":[[2024,4]]}},"alternative-id":["10.1136\/bcr-2023-258688"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2023-258688","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2024,4]]}}}