{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T17:10:02Z","timestamp":1756314602401,"version":"3.44.0"},"reference-count":12,"publisher":"BMJ","issue":"2","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,1,28]]},"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:p>A South Asian male in his early 60s presented with acute-onset dyspnoea on postoperative day 4 after undergoing middle hepatic vein sacrificing partial liver resection for epithelioid angiomyolipoma. The patient\u2019s SpO<jats:sub>2<\/jats:sub> on presentation was 65% in standing position which improved to 90% in left lateral decubitus. He was suspected of having platypnea\u2013orthodeoxia syndrome (POS) which was confirmed on echocardiogram with microbubble contrast showing a large intracardiac right-to-left shunt. The patient was taken up for transcatheter closure of patent foramen ovale (PFO). A 30\u2009mm Amplatzer PFO Occluder was deployed across the PFO which reduced the intracardiac shunt resulting in an improved arterial saturation as well as immediate relief of patient\u2019s symptoms. This case illustrates the importance of suspecting and recognising POS clinically as well as the efficacy of transcatheter closure of PFO in such cases leading to resolution of hypoxaemia in a short span of time.<\/jats:p>","DOI":"10.1136\/bcr-2023-258755","type":"journal-article","created":{"date-parts":[[2024,2,8]],"date-time":"2024-02-08T01:35:15Z","timestamp":1707356115000},"page":"e258755","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Platypnea\u2013orthodeoxia syndrome (POS) in a patient who had undergone partial liver resection"],"prefix":"10.1136","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3298-6217","authenticated-orcid":false,"given":"Bhavik Sandip","family":"Shah","sequence":"first","affiliation":[{"name":"Cardiology, KEM Hospital and Seth G S Medical College, Mumbai, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Girish Ramkrishna","family":"Sabnis","sequence":"additional","affiliation":[{"name":"Cardiology, KEM Hospital and Seth G S Medical College, Mumbai, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1932-4318","authenticated-orcid":false,"given":"Dhiraj","family":"Kumar","sequence":"additional","affiliation":[{"name":"Cardiology, KEM Hospital and Seth G S Medical College, Mumbai, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charan","family":"Lanjewar","sequence":"additional","affiliation":[{"name":"Cardiology, KEM Hospital and Seth G S Medical College, Mumbai, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,2,7]]},"reference":[{"key":"2025082709303807000_17.2.e258755.1","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.rmed.2017.05.016","article-title":"The multiple dimensions of Platypnea-Orthodeoxia syndrome: a review","volume":"129","author":"Agrawal","year":"2017","journal-title":"Respir Med"},{"key":"2025082709303807000_17.2.e258755.2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196912112812408"},{"key":"2025082709303807000_17.2.e258755.3","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1056\/NEJM197604222941711","article-title":"Platypnea related to orthodeoxia caused by true vascular lung shunts","volume":"294","author":"Robin","year":"1976","journal-title":"N Engl J Med"},{"key":"2025082709303807000_17.2.e258755.4","doi-asserted-by":"crossref","unstructured":"Seward JB , Hayes DL , Smith HC , et al . 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The hepatic artery, portal venous system and portal hypertension: the hepatic veins and liver in circulatory failure. In: Dooley JS , Lok ASF , Burroughs AK , et al ., eds. Sherlock\u2019s Diseases of the Liver and Biliary System [Internet]. 1st ed. 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