{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T14:40:06Z","timestamp":1756305606312,"version":"3.44.0"},"reference-count":12,"publisher":"BMJ","issue":"5","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,4,20]]},"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:p>A non-diabetic woman in her 80s presented 1\u2009week following uncomplicated left eye cataract surgery complaining of decreased vision, gritty sensation and photophobia in the same eye. Postoperative treatment included G. Acular (Ketorolac Tromethamine 0.5%, NSAID: non-steroidal anti-inflammatory drug) and G. Tobradex (Tobramycin 0.3% and Dexamethasone 0.1%, antibiotic and steroid, respectively) each prescribed four times a day for 2\u2009weeks. On examination, the patient had a corneal epithelial defect which progressed to a full-thickness perforation despite ceasing the NSAID drops. Cyanoacrylate glue application with a plastic drape patch failed to seal the perforation, and a full-thickness tectonic corneal transplant was performed. On investigation, the patient had positive anti-RO and anti-LA antibodies, suggesting a diagnosis of Sj\u00f6gren\u2019s syndrome. We advocate for careful preoperative assessment prior to cataract surgery, patient education, close follow-up and cautious medication use postoperatively including avoiding NSAID drops in patients with risk factors for postoperative dry eye disease.<\/jats:p>","DOI":"10.1136\/bcr-2023-258829","type":"journal-article","created":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T23:46:17Z","timestamp":1716421577000},"page":"e258829","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["NSAID-induced corneal melt as the first presentation of Sj\u00f6gren\u2019s syndrome"],"prefix":"10.1136","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7209-9877","authenticated-orcid":false,"given":"Mustafa","family":"Hammad","sequence":"first","affiliation":[{"name":"General Surgery, West Suffolk NHS Foundation Trust, Bury Saint Edmunds, UK"},{"name":"Royal College of Surgeons in Ireland Medical University of Bahrain, Muharraq, Bahrain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lubna","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Ophthalmology, Northampton General Hospital NHS Trust, Northampton, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9232-4923","authenticated-orcid":false,"given":"Mohamed","family":"Seifelnasr","sequence":"additional","affiliation":[{"name":"Ophthalmology, York Teaching Hospital NHS Foundation Trust, York, UK"},{"name":"Ophthalmology, Alexandria University, Alexandria, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,5,22]]},"reference":[{"key":"2025082707022058000_17.5.e258829.1","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1159\/000455280","article-title":"Postsurgical cystoid macular edema","volume":"58","author":"Zur","year":"2017","journal-title":"Dev 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