{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T18:37:56Z","timestamp":1785350276418,"version":"3.55.0"},"reference-count":11,"publisher":"BMJ","issue":"7","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,6,19]]},"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:p>A woman in her mid-20s, a known case of congenital afibrinogenaemia, presented with abdominal pain and distension. She was diagnosed with decompensated liver cirrhosis due to Budd-Chiari syndrome. She underwent deceased donor liver transplantation. Preoperatively, her serum fibrinogen level was undetectable and prothrombin time and international normalised ratio (INR) were unrecordable. Intraoperatively, she was given thromboelastography-guided human fibrinogen concentrate. Postoperatively, her fibrinogen, prothrombin time and INR normalised rapidly. This report summarises the rare occurrence of a complication of hypercoagulability (Budd-Chiari syndrome) in the setting of congenital hypocoagulability (congenital afibrinogenaemia). In this report, we discuss the simultaneous management of these two clinical problems and the curative role of liver transplantation.<\/jats:p>","DOI":"10.1136\/bcr-2023-259078","type":"journal-article","created":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T14:45:28Z","timestamp":1720017928000},"page":"e259078","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Budd-Chiari syndrome associated with congenital afibrinogenaemia reversed after orthotopic liver transplant"],"prefix":"10.1136","volume":"17","author":[{"given":"Vinayak G","family":"Nikam","sequence":"first","affiliation":[{"name":"HPB and Liver Transplant Surgery, Kokilaben Dhirubhai Ambani Hospital, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1083-3458","authenticated-orcid":false,"given":"Vijay 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