{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:03:31Z","timestamp":1756425811186,"version":"3.44.0"},"reference-count":13,"publisher":"BMJ","issue":"6","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,5,17]]},"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:p>Intracardiac lymphomas are exceedingly rare accounting for only 1% of all primary cardiac tumours. Historically, due to their insidious development and non-specific clinical presentation, the diagnosis has been challenging with most cases being confirmed on post-mortem examination. Our case report details the experience of a previously fit and active woman in her 60s who presented with gradual onset exertional dyspnoea. Through a series of multimodal imaging tools (including echocardiogram, cardiac MRI, CT and positron emission tomography-CT) and biopsy, we confirmed the diagnosis of intracardiac diffuse large B-cell lymphoma. Our patient was managed with chemotherapy and went on to demonstrate excellent radiological response with near-complete resolution of the intracardiac mass. Subjectively, our patient reported significant improvement in exercise tolerance within weeks of commencing treatment.<\/jats:p>","DOI":"10.1136\/bcr-2023-259242","type":"journal-article","created":{"date-parts":[[2024,6,24]],"date-time":"2024-06-24T22:45:13Z","timestamp":1719269113000},"page":"e259242","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Intracardiac diffuse large B-cell lymphoma: an unexpected diagnosis"],"prefix":"10.1136","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2427-0449","authenticated-orcid":false,"given":"Komeil","family":"Alattar","sequence":"first","affiliation":[{"name":"Darent Valley Hospital, Dartford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sagar","family":"Dodhia","sequence":"additional","affiliation":[{"name":"Darent Valley Hospital, Dartford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chieh-Yin","family":"Huang","sequence":"additional","affiliation":[{"name":"Darent Valley Hospital, Dartford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joana Briosa","family":"Neves","sequence":"additional","affiliation":[{"name":"Guy's and St Thomas' NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arafat","family":"Haris","sequence":"additional","affiliation":[{"name":"Darent Valley Hospital, Dartford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,6,24]]},"reference":[{"key":"2025082801554819000_17.6.e259242.1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdp424"},{"key":"2025082801554819000_17.6.e259242.2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1827.2003.01606.x"},{"key":"2025082801554819000_17.6.e259242.3","doi-asserted-by":"publisher","DOI":"10.1080\/10428190310001617259"},{"key":"2025082801554819000_17.6.e259242.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2010.02.016"},{"key":"2025082801554819000_17.6.e259242.5","doi-asserted-by":"crossref","DOI":"10.1186\/s13019-015-0348-0","article-title":"Primary cardiac lymphoma: two cases and a review of literature","volume":"10","author":"Jonavicius","year":"2015","journal-title":"J Cardiothorac Surg"},{"key":"2025082801554819000_17.6.e259242.6","unstructured":"WHO Classification of Tumours Editorial Board . Haematolymphoid tumours [Internet; beta version ahead of print]. Lyon (France): International Agency for Research on Cancer; 2022 [cited 2024 February 21]. (WHO classification of tumours series, 5th ed.; vol. 11), 2022. Available: https:\/\/tumourclassification.iarc.who.int\/chapters\/63"},{"key":"2025082801554819000_17.6.e259242.7","unstructured":"WHO Classification of Tumours Editorial Board . Thoracic tumours. Lyon (France): International Agency for Research on Cancer; 2021 [cited 2024 February 21]. (WHO classification of tumours series, 5th ed.; vol. 5), Available: https:\/\/tumourclassification.iarc.who.int\/chapters\/35"},{"key":"2025082801554819000_17.6.e259242.8","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(05)70093-0"},{"key":"2025082801554819000_17.6.e259242.9","doi-asserted-by":"publisher","DOI":"10.1136\/heart.85.2.218"},{"key":"2025082801554819000_17.6.e259242.10","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.25444"},{"key":"2025082801554819000_17.6.e259242.11","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1177\/000331970305400510","article-title":"Clinical perspectives of primary cardiac lymphoma","volume":"54","author":"Gowda","year":"2003","journal-title":"Angiology"},{"key":"2025082801554819000_17.6.e259242.12","doi-asserted-by":"crossref","DOI":"10.17795\/ijcp-3913","article-title":"Cardiac involvement in non-Hodgkin lymphoma, an incidental large atrial mass: A case report","volume":"8","author":"Aledavood","year":"2015","journal-title":"Iran J Cancer Prev"},{"key":"2025082801554819000_17.6.e259242.13","first-page":"74","article-title":"Large B-cell lymphoma of the Atria","volume":"30","author":"Alzeerah","year":"2003","journal-title":"Tex Heart Inst J"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2023-259242","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T08:55:56Z","timestamp":1756371356000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2023-259242"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":13,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2024,6,24]]},"published-print":{"date-parts":[[2024,6]]}},"alternative-id":["10.1136\/bcr-2023-259242"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2023-259242","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2024,6]]}}}