{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T21:55:22Z","timestamp":1791669322557,"version":"4.3.4"},"reference-count":9,"publisher":"BMJ","issue":"6","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,6,10]]},"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:p>This case report describes a man in his 20s presenting with bilateral crypto-orchidism, micropenis and underdeveloped secondary sexual characteristics. The patient also exhibited hyposmia, eunuchoid stature and gynecomastia. Biochemical investigations revealed low levels of testosterone, luteinising hormone and follicle-stimulating hormone. Hence, he was diagnosed with Kallmann syndrome. Imaging studies showed an absent right kidney and cystic dilatation of the distal ureteric bud, seminal vesicle and absent\/hypoplastic ejaculatory duct. The association of hypogonadotropic hypogonadism with Zinner syndrome, a rare condition characterised by renal agenesis, seminal vesicle cyst and ejaculatory duct obstruction, was noted.<\/jats:p>","DOI":"10.1136\/bcr-2023-259363","type":"journal-article","created":{"date-parts":[[2024,6,20]],"date-time":"2024-06-20T03:55:39Z","timestamp":1718855739000},"page":"e259363","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Hypogonadotropic hypogonadism with Zinner syndrome: a coincidence or a consequence?"],"prefix":"10.1136","volume":"17","author":[{"given":"Ravi","family":"Shah","sequence":"first","affiliation":[{"name":"Endocrinology, Post Graduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soham","family":"Mukherjee","sequence":"additional","affiliation":[{"name":"Endocrinology, Post Graduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0410-8778","authenticated-orcid":false,"given":"Sanjay Kumar","family":"Bhadada","sequence":"additional","affiliation":[{"name":"Endocrinology, Post Graduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rama","family":"Walia","sequence":"additional","affiliation":[{"name":"Endocrinology, Post Graduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2024,6,19]]},"reference":[{"key":"2025082622542128000_17.6.e259363.1","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1590\/S0004-27302008000100004","article-title":"Kallmann syndrome: a historical corrected clinical and molecular review","volume":"52","author":"Ribeiro","year":"2008","journal-title":"Arq Bras Endocrinol Metabol"},{"key":"2025082622542128000_17.6.e259363.2","first-page":"216","article-title":"A family with novel X-linked recessive homozygous mutation in Anos1 (C.628_629 del, P.1210Fs\u2217) in kallmann syndrome associated unilateral Ptosis: case report and literature review","volume":"7","author":"Noorian","year":"2021","journal-title":"AACE Clin Case Rep"},{"key":"2025082622542128000_17.6.e259363.3","unstructured":"Sonne J , Lopez-Ojeda W . Kallmann syndrome. In: StatPearls. Treasure Island (FL): StatPearls Publishing, 2023. Available: http:\/\/www.ncbi.nlm.nih.gov\/books\/NBK538210\/"},{"key":"2025082622542128000_17.6.e259363.4","unstructured":"Zinner A . Ein fall von Intravesikaler Samenblasenzyste. Wien Med Wochenschr 1914;64."},{"key":"2025082622542128000_17.6.e259363.5","doi-asserted-by":"publisher","DOI":"10.1159\/000019632"},{"key":"2025082622542128000_17.6.e259363.6","unstructured":"Robertson RP . Degroot\u2019s Endocrinology: Degroot\u2019s Endocrinology, E-Book. Elsevier Health Sciences, 2022:2539."},{"key":"2025082622542128000_17.6.e259363.7","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1111\/j.1399-0004.1994.tb04238.x","article-title":"Unilateral renal aplasia in X-linked kallmann\u2019s syndrome","volume":"46","author":"Kirk","year":"1994","journal-title":"Clinical Genetics"},{"key":"2025082622542128000_17.6.e259363.8","doi-asserted-by":"crossref","first-page":"2271","DOI":"10.21037\/apm-20-1997","article-title":"Zinner syndrome: an updated pooled analysis based on 214 cases from 1999 to 2020: a systematic review","volume":"10","author":"Liu","year":"2021","journal-title":"Ann Palliat Med"},{"key":"2025082622542128000_17.6.e259363.9","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/s11701-013-0430-3","article-title":"Robot-assisted management of Zinner\u2019s syndrome: report of seminal vesicle sparing technique and review of the literature","volume":"8","author":"Sridhar","year":"2014","journal-title":"J Robot Surg"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2023-259363","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T05:54:32Z","timestamp":1756274072000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2023-259363"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":9,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2024,6,19]]},"published-print":{"date-parts":[[2024,6]]}},"alternative-id":["10.1136\/bcr-2023-259363"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2023-259363","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6]]}}}