{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T20:40:06Z","timestamp":1756327206253,"version":"3.44.0"},"reference-count":9,"publisher":"BMJ","issue":"2","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,2,4]]},"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:p>Thrombosis and thrombophlebitis of the facial vein represent exceptionally rare diagnoses, particularly when occurring as complications of acute sialadenitis of the submandibular gland. This case report details the experience of a middle-aged man initially presenting at a tertiary care ear, nose and throat department with right submandibular gland sialadenitis. Despite initiating outpatient treatment involving oral antibiotics and sialagogues, the patient returned after a week with persistent and worsening pain, accompanied by swelling of the right submandibular gland and cheek. Using ultrasound, the accurate diagnosis was promptly identified, revealing thrombosis in the facial vein.<\/jats:p>\n               <jats:p>The patient underwent a comprehensive treatment regimen involving anticoagulation and intravenous antibiotics. With a subsequent reduction in pain and swelling, the patient was discharged, continuing oral anticoagulation and antibiotics. Outpatient follow-up revealed a complete recovery 3\u2009weeks later. This case underscores the importance of timely and precise diagnostic measures in managing rare complications associated with sialadenitis.<\/jats:p>","DOI":"10.1136\/bcr-2023-259423","type":"journal-article","created":{"date-parts":[[2024,2,13]],"date-time":"2024-02-13T12:26:20Z","timestamp":1707827180000},"page":"e259423","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Rare encounter: facial vein thrombosis and thrombophlebitis as a complication of acute submandibular sialadenitis"],"prefix":"10.1136","volume":"17","author":[{"given":"Frieder","family":"Goebel","sequence":"first","affiliation":[{"name":"Otorhinolaryngology and head and neck surgery, SLK-Kliniken Heilbronn GmbH, Heilbronn, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katrin","family":"Knopf","sequence":"additional","affiliation":[{"name":"Otorhinolaryngology and head and neck surgery, SLK-Kliniken Heilbronn GmbH, Heilbronn, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9319-8260","authenticated-orcid":false,"given":"Lukas S","family":"Fiedler","sequence":"additional","affiliation":[{"name":"Otorhinolaryngology and head and neck surgery, SLK-Kliniken Heilbronn GmbH, Heilbronn, Germany"},{"name":"Faculty of Medicine, Heidelberg University, Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,2,13]]},"reference":[{"key":"2025082713221209000_17.2.e259423.1","doi-asserted-by":"crossref","unstructured":"Probst R , Grevers G , Iro H . The salivary glands. In: Basic Otorhinolaryngology: A Step-by-Step Learning Guide. Stuttgart: Thieme, 2017.","DOI":"10.1055\/b-005-148915"},{"key":"2025082713221209000_17.2.e259423.2","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1177\/1971400916682752","article-title":"Imaging of sialadenitis","volume":"30","author":"Abdel Razek","year":"2017","journal-title":"Neuroradiol J"},{"key":"2025082713221209000_17.2.e259423.3","doi-asserted-by":"crossref","unstructured":"Dunnebier EA . Imaging for otolaryngologists. Thieme, 2011.","DOI":"10.1055\/b-002-74274"},{"key":"2025082713221209000_17.2.e259423.4","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1007\/s00247-014-3272-x","article-title":"Facial vein thrombophlebitis: an uncommon complication of sinusitis","volume":"45","author":"Cotes","year":"2015","journal-title":"Pediatr Radiol"},{"key":"2025082713221209000_17.2.e259423.5","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2009.317"},{"key":"2025082713221209000_17.2.e259423.6","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.ijporl.2018.08.015","article-title":"Facial vein thrombophlebitis: a case report and literature review","volume":"113","author":"Paker","year":"2018","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"2025082713221209000_17.2.e259423.7","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/s00106-003-0846-6","article-title":"Lemierre-syndrom","volume":"52","author":"Sagowski","year":"2004","journal-title":"HNO"},{"key":"2025082713221209000_17.2.e259423.8","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.ijporl.2016.06.013","article-title":"To anticoagulate? Controversy in the management of thrombotic complications of head & neck infections","volume":"88","author":"Rebelo","year":"2016","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"2025082713221209000_17.2.e259423.9","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1177\/1060028020957620","article-title":"Anticoagulation strategies in the management of lemierre syndrome: a systematic review of the literature","volume":"55","author":"Adedeji","year":"2021","journal-title":"Ann Pharmacother"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2023-259423","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T20:22:18Z","timestamp":1756326138000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2023-259423"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2]]},"references-count":9,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2024,2,13]]},"published-print":{"date-parts":[[2024,2]]}},"alternative-id":["10.1136\/bcr-2023-259423"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2023-259423","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2024,2]]}}}