{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:05:31Z","timestamp":1756339531300,"version":"3.44.0"},"reference-count":21,"publisher":"BMJ","issue":"6","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,5,17]]},"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:p>The risks and benefits of spinal anaesthesia must be assessed in patients with coagulation disorders. A woman in her 20s with congenital factor VII (FVII) deficiency (31%) was admitted at 38 weeks for caesarean delivery. A rotational thromboelastometry (ROTEM) analysis showed normal coagulation and spinal anaesthesia was performed safely. A repeated ROTEM analysis after haemostasis and uterine closure showed normal coagulation without fibrinolysis. No prophylactic FVII was administered, resulting in a cost savings of US$12\u2009884. FVII level did not predict bleeding or fibrinolysis and FVII and tranexamic acid were not indicated.<\/jats:p>","DOI":"10.1136\/bcr-2023-259464","type":"journal-article","created":{"date-parts":[[2024,6,20]],"date-time":"2024-06-20T03:55:40Z","timestamp":1718855740000},"page":"e259464","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Viscoelastic testing guided coagulation management in factor VII deficiency for spinal anaesthesia and caesarean section"],"prefix":"10.1136","volume":"17","author":[{"given":"Uzung","family":"Yoon","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shannon","family":"Haley","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzanne","family":"Huffnagle","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jane","family":"Huffnagle","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,6,19]]},"reference":[{"key":"2025082709153172000_17.6.e259464.1","article-title":"The effect of spinal versus general anesthesia on quality of life in women undergoing cesarean delivery on maternal request","volume":"10","author":"Ghaffari","year":"2018","journal-title":"Cureus"},{"key":"2025082709153172000_17.6.e259464.2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2011.04291.x"},{"key":"2025082709153172000_17.6.e259464.3","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1159\/000217259","article-title":"Treatment of factor VII deficiency with recombinant factor Vila","volume":"26","author":"Bauer","year":"1996","journal-title":"Pathophysiol Haemos Thromb"},{"key":"2025082709153172000_17.6.e259464.4","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1111\/bjh.14148","article-title":"The utility of Thromboelastography in inherited and acquired bleeding disorders","volume":"174","author":"Nogami","year":"2016","journal-title":"Br J Haematol"},{"key":"2025082709153172000_17.6.e259464.5","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1177\/10892532231151528","article-title":"Native whole blood (TRUE-NATEM) and recalcified citrated blood (NATEM) reference value validation with ROTEM Delta","volume":"27","author":"Yoon","year":"2023","journal-title":"Semin Cardiothorac Vasc Anesth"},{"key":"2025082709153172000_17.6.e259464.6","doi-asserted-by":"crossref","DOI":"10.12659\/AJCR.930245","article-title":"Severe congenital factor VII deficiency with normal perioperative coagulation profile based on ROTEM analysis in a hepatectomy","volume":"22","author":"Yeom","year":"2021","journal-title":"Am J Case Rep"},{"key":"2025082709153172000_17.6.e259464.7","unstructured":"Label. 2023. 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