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Following hospitalisation for treatment of right deltoid pyomyositis caused by <jats:italic>Salmonella enterica<\/jats:italic> serovar Enteritidis with intravenous antibiotics, he was subsequently re-admitted when an MRI scan identified new osteomyelitis of the proximal right humerus, an associated abscess within the bone and persistent pyomyositis of the right deltoid. He was managed with surgical irrigation and debridement, followed by a 6-week course of parenteral antibiotics.<\/jats:p>\n               <jats:p>Osteoarticular infections with suppurative complications caused by <jats:italic>Salmonella<\/jats:italic> species are extremely rare in immune-competent infants. Risk factors for <jats:italic>Salmonella<\/jats:italic> infections include sick contacts, residing in a rural area, recent travel to regions of high exposure and reptile exposure. Invasive nontyphoidal Salmonellosis should be considered in children with musculoskeletal complaints after recent <jats:italic>Salmonella<\/jats:italic> gastrointestinal infections. Treatment may require both surgical source control and 4\u20136 weeks of antibiotic therapy.<\/jats:p>","DOI":"10.1136\/bcr-2024-259722","type":"journal-article","created":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T15:10:22Z","timestamp":1744816222000},"page":"e259722","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Nontyphoidal <i>Salmonella<\/i> pyomyositis and osteomyelitis in a healthy infant"],"prefix":"10.1136","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7883-4748","authenticated-orcid":false,"given":"Matthew","family":"Penfold","sequence":"first","affiliation":[{"name":"Department of Paediatrics, Walter Reed National Military Medical Centre, Bethesda, Maryland, USA"},{"name":"Department of Paediatrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margaret","family":"Hasler","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Walter Reed National Military Medical Centre, Bethesda, Maryland, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Rahman","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Walter Reed National Military Medical Centre, Bethesda, Maryland, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alison","family":"Helfrich","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Walter Reed National Military Medical Centre, Bethesda, Maryland, USA"},{"name":"Department of Paediatrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,4,16]]},"reference":[{"key":"2025082711224428000_18.4.e259722.1","unstructured":"Cherry JD , Harrison GJ , Kaplan SL , et al . 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