{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:06:52Z","timestamp":1756339612225,"version":"3.44.0"},"reference-count":17,"publisher":"BMJ","issue":"6","license":[{"start":{"date-parts":[[2024,6,18]],"date-time":"2024-06-18T00:00:00Z","timestamp":1718668800000},"content-version":"unspecified","delay-in-days":17,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,5,12]]},"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:p>We introduce the case of a male patient in his 60s who was admitted to our emergency department with a persisting sore throat for the last 3\u2009weeks and dysphagia. Fibre-endoscopic evaluation revealed an asymmetry at the base of the tongue. In combination with elevated white cell count and C reactive protein, a computerized tomography showed a superinfected thyroglossal duct cyst. Intravenous antibiotics were initiated, and the patient was taken to the operating room for cervicotomy. The microbiological swab taken intraoperatively detected <jats:italic>Nocardia paucivorans<\/jats:italic>. Additional imaging revealed disseminated nocardiosis with cerebral and pulmonary manifestations.<\/jats:p>\n               <jats:p>The patient was treated with oral trimethoprim\/sulfamethoxazole and, over time, showed complete remission of central nervous system lesions and improvement of pulmonary involvement. Following this, the treatment was stopped 8\u2009months after the initial diagnosis. In this report, we discuss treatment standards and outcomes of nocardiosis based on our management strategies of our patient.<\/jats:p>","DOI":"10.1136\/bcr-2024-259725","type":"journal-article","created":{"date-parts":[[2024,6,18]],"date-time":"2024-06-18T22:35:15Z","timestamp":1718750115000},"page":"e259725","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Disseminated nocardiosis presenting as a superinfected thyroglossal duct cyst in a patient with diabetes"],"prefix":"10.1136","volume":"17","author":[{"given":"Anouk","family":"Schmid","sequence":"first","affiliation":[{"name":"HNO, Kantonsspital Aarau AG, Aarau, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nader","family":"Ahmad","sequence":"additional","affiliation":[{"name":"HNO, Kantonsspital Aarau AG, Aarau, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastian","family":"Haubitz","sequence":"additional","affiliation":[{"name":"Infektiologie, Kantonsspital Aarau AG, Aarau, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1113-0575","authenticated-orcid":false,"given":"Marlene Maria","family":"Speth","sequence":"additional","affiliation":[{"name":"University Hospital Basel, Basel, Switzerland"},{"name":"Kantonsspital Aarau AG, Aarau, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,6,18]]},"reference":[{"key":"2025082713152912000_17.6.e259725.1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.19.2.259-282.2006"},{"key":"2025082713152912000_17.6.e259725.2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/134.3.286"},{"key":"2025082713152912000_17.6.e259725.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2011.11.016"},{"key":"2025082713152912000_17.6.e259725.4","doi-asserted-by":"crossref","unstructured":"Li F , Wang J , Chen C , et al . 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Susceptibility testing of mycobacteria, nocardiae, and other aerobic actinomycetes. 2nd edn. 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