{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:03:45Z","timestamp":1756425825483,"version":"3.44.0"},"reference-count":12,"publisher":"BMJ","issue":"5","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,5,21]]},"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:p>A woman in her 40s presented with thoracic banding dysaesthesia and lower motor neuron weakness. Spinal imaging revealed a short segment of transverse myelitis and neurophysiology was suggestive of concurrent acute inflammatory demyelinating polyneuropathy. The patient improved with consecutive intravenous immunoglobulin and methylprednisolone treatment. Acute inflammatory demyelinating polyneuropathy is a progressive immune-mediated peripheral neuropathy which responds to intravenous immunoglobulin or plasmapheresis, whereas transverse myelitis is a central inflammatory syndrome usually treated with corticosteroid. We highlight differentiating features of the clinical presentation and the utility of investigations such as neurophysiology and MRI along with a review of treatment and the role for corticosteroid therapy.<\/jats:p>","DOI":"10.1136\/bcr-2024-259732","type":"journal-article","created":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T22:35:30Z","timestamp":1716935730000},"page":"e259732","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Concurrent transverse myelitis and acute inflammatory demyelinating polyneuropathy"],"prefix":"10.1136","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-2345-2806","authenticated-orcid":false,"given":"Matthew","family":"Shrimpton","sequence":"first","affiliation":[{"name":"Neurology Department, Barwon Health, Geelong, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cameron","family":"Shaw","sequence":"additional","affiliation":[{"name":"Neurology Department, Barwon Health, Geelong, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,5,28]]},"reference":[{"doi-asserted-by":"publisher","key":"2025082802512683000_17.5.e259732.1","DOI":"10.1016\/S0140-6736(16)00339-1"},{"doi-asserted-by":"publisher","key":"2025082802512683000_17.5.e259732.2","DOI":"10.1212\/WNL.59.4.499"},{"doi-asserted-by":"publisher","key":"2025082802512683000_17.5.e259732.3","DOI":"10.1212\/WNL.56.8.1104"},{"doi-asserted-by":"publisher","key":"2025082802512683000_17.5.e259732.4","DOI":"10.1016\/S1474-4422(08)70215-1"},{"doi-asserted-by":"publisher","key":"2025082802512683000_17.5.e259732.5","DOI":"10.1016\/J.NCL.2012.09.008"},{"key":"2025082802512683000_17.5.e259732.6","doi-asserted-by":"crossref","first-page":"S161","DOI":"10.3345\/kjp.2016.59.11.S161","article-title":"Concurrency of Guillain-Barre syndrome and acute transverse Myelitis: a case report and review of literature","volume":"59","author":"Tolunay","year":"2016","journal-title":"Korean J Pediatr"},{"key":"2025082802512683000_17.5.e259732.7","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1097\/CM9.0000000000002662","article-title":"Concomitant transverse Myelitis and Guillain-Barre syndrome following Varicella-Zoster virus infection","volume":"136","author":"Lan","year":"2023","journal-title":"Chin Med J (Engl)"},{"key":"2025082802512683000_17.5.e259732.8","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2021-246967","article-title":"A possible Guillain-Barre syndrome\/transverse Myelitis overlap syndrome after recent COVID-19","volume":"15","author":"Alrubaye","year":"2022","journal-title":"BMJ Case Rep"},{"doi-asserted-by":"publisher","key":"2025082802512683000_17.5.e259732.9","DOI":"10.1136\/jnnp.2008.148213"},{"key":"2025082802512683000_17.5.e259732.10","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2023.1288546","article-title":"Combined central and peripheral Demyelination: a case report resembling Encephalomyeloradiculoneuropathy","volume":"14","author":"Zhou","year":"2023","journal-title":"Front Neurol"},{"key":"2025082802512683000_17.5.e259732.11","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1179\/1743132814Y.0000000400","article-title":"Clinical characteristics and outcomes of patients with Guillain-Barre and acquired CNS Demyelinating overlap syndrome: a cohort study based on a literature review","volume":"36","author":"Mao","year":"2014","journal-title":"Neurol Res"},{"key":"2025082802512683000_17.5.e259732.12","article-title":"Corticosteroids for Guillain-Barre syndrome","volume":"10","author":"Hughes","year":"2016","journal-title":"Cochrane Database Syst Rev"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2024-259732","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:51:32Z","timestamp":1756374692000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2024-259732"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":12,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2024,5,28]]},"published-print":{"date-parts":[[2024,5]]}},"alternative-id":["10.1136\/bcr-2024-259732"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2024-259732","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2024,5]]}}}