{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T04:00:18Z","timestamp":1790827218938,"version":"4.1.0"},"reference-count":12,"publisher":"BMJ","issue":"4","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,4,18]]},"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:p>Catheter-related bloodstream infection (CRBSI) is one of the common healthcare-acquired infections imposing a high burden of morbidity and mortality on the patients. Non-tuberculous mycobacterium is a rare aetiology for CRBSI and poses challenges in laboratory diagnosis and clinical management. This is a case of a woman in her early 60s with underlying end-stage renal failure, diabetes mellitus and hypertension presented with a 2-week history of high-grade fever postregular haemodialysis, vomiting, lethargy and altered mental status.<\/jats:p>\n               <jats:p>Blood cultures from a permanent catheter and peripheral taken concurrently yielded <jats:italic>Mycobacterium senegalense<\/jats:italic>, identified by matrix-assisted laser desorption\/ionisation time-of-flight mass spectrometry, which established the diagnosis of CRBSI atypically presented with concurrent acute intracranial bleeding and cerebrovascular infarction at initial presentation. She was started on a combination of oral azithromycin, oral amikacin and intravenous imipenem, and the permanent catheter was removed. Despite the treatments instituted, she developed septicaemia, acute myocardial infarction and macrophage activation-like syndrome, causing the patient\u2019s death.<\/jats:p>","DOI":"10.1136\/bcr-2024-259761","type":"journal-article","created":{"date-parts":[[2024,4,30]],"date-time":"2024-04-30T11:57:29Z","timestamp":1714478249000},"page":"e259761","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["<i>Mycobacterium senegalense<\/i> catheter-related bloodstream infection"],"prefix":"10.1136","volume":"17","author":[{"given":"Noralwani","family":"Badarol Hisham","sequence":"first","affiliation":[{"name":"Department of Medical Microbiology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia"},{"name":"Department of Pathology, Hospital Kuala Lumpur, Wilayah Persekutuan Kuala Lumpur, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mazriza","family":"Madon","sequence":"additional","affiliation":[{"name":"Department of Pathology, Hospital Kuala Lumpur, Wilayah Persekutuan Kuala Lumpur, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siti Norbaya","family":"Masri","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia"},{"name":"Hospital Sultan Abdul Aziz Shah, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6054-2368","authenticated-orcid":false,"given":"Syafinaz","family":"Amin-Nordin","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia"},{"name":"Hospital Sultan Abdul Aziz Shah, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia"},{"name":"Institute of Bioscience, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2024,4,30]]},"reference":[{"key":"2025082703333055000_17.4.e259761.1","doi-asserted-by":"crossref","first-page":"185","DOI":"10.4103\/ijmr.IJMR_902_20","article-title":"Epidemiology, diagnosis & treatment of non-tuberculous Mycobacterial diseases","volume":"152","author":"Sharma","year":"2020","journal-title":"Indian J Med 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fish tank exposure","volume":"22","author":"Talavlikar","year":"2011","journal-title":"Can J Infect Dis Med Microbiol"},{"key":"2025082703333055000_17.4.e259761.7","doi-asserted-by":"crossref","first-page":"899846","DOI":"10.3389\/fpubh.2022.899846","article-title":"Case report: mycobacterium senegalense infection after cholecystectomy","volume":"10","author":"Zhou","year":"2022","journal-title":"Front Public Health"},{"key":"2025082703333055000_17.4.e259761.8","doi-asserted-by":"crossref","first-page":"611","DOI":"10.3201\/eid2603.190230","article-title":"Mycobacterium senegalense infection after implant-based breast reconstruction, Spain","volume":"26","author":"Carretero","year":"2020","journal-title":"Emerg Infect Dis"},{"key":"2025082703333055000_17.4.e259761.9","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0114428","article-title":"Molecular epidemiology of nontuberculous mycobacteria isolates from clinical and environmental sources of a metropolitan city","volume":"9","author":"Akbar Velayati","year":"2014","journal-title":"PLoS One"},{"key":"2025082703333055000_17.4.e259761.10","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.120.030429"},{"key":"2025082703333055000_17.4.e259761.11","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2019.00055","article-title":"Macrophage activation-like syndrome: a distinct entity leading to early death in sepsis","volume":"10","author":"Karakike","year":"2019","journal-title":"Front Immunol"},{"key":"2025082703333055000_17.4.e259761.12","doi-asserted-by":"crossref","DOI":"10.1186\/s12879-019-4061-9","article-title":"Nontuberculous Mycobacterium infection complicated with Haemophagocytic syndrome: a case report and literature review","volume":"19","author":"Shi","year":"2019","journal-title":"BMC Infect Dis"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2024-259761","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T10:33:38Z","timestamp":1756290818000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2024-259761"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":12,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2024,4,30]]},"published-print":{"date-parts":[[2024,4]]}},"alternative-id":["10.1136\/bcr-2024-259761"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2024-259761","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4]]}}}