{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T06:10:10Z","timestamp":1756361410111,"version":"3.44.0"},"reference-count":12,"publisher":"BMJ","issue":"7","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,7,7]]},"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:p>This case report delves into the diagnostic intricacies and clinical management of adult granulosa cell tumour (AGCT) in a woman in her 50s, presenting with pain abdomen. Initial imaging investigations like ultrasound suggested diagnosis of benign cystadenoma. Further MRI revealed a large well-defined multiloculated lesion so a diagnosis of neoplastic aetiology\/likely mucinous cystadenocarcinoma was offered. However, the definitive diagnosis was established through meticulous histopathological examination, revealing characteristic features of AGCT, a rare ovarian neoplasm. The case underscores the diagnostic challenges posed by AGCT, the importance of integrating clinical, radiological and histopathological data, and the necessity for a multidisciplinary approach for accurate diagnosis and optimal patient management.<\/jats:p>","DOI":"10.1136\/bcr-2024-259788","type":"journal-article","created":{"date-parts":[[2024,7,16]],"date-time":"2024-07-16T22:00:24Z","timestamp":1721167224000},"page":"e259788","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Adult granulosa cell tumour camouflaged as mucinous neoplasm"],"prefix":"10.1136","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4523-7274","authenticated-orcid":false,"given":"Savitri M","family":"Nerune","sequence":"first","affiliation":[{"name":"Pathology, Shri B.M. Patil Medical College, Hospital and Research Centre, BLDE (Deemed to be University), Vijayapura, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-4839-9152","authenticated-orcid":false,"given":"Sayandeep K","family":"Das","sequence":"additional","affiliation":[{"name":"Pathology, Shri B.M. Patil Medical College, Hospital and Research Centre, BLDE (Deemed to be University), Vijayapura, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monika","family":"Pawar","sequence":"additional","affiliation":[{"name":"Pathology, Shri B.M. Patil Medical College, Hospital and Research Centre, BLDE (Deemed to be University), Vijayapura, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,7,16]]},"reference":[{"key":"2025082722464310000_17.7.e259788.1","doi-asserted-by":"crossref","DOI":"10.1186\/s13048-020-00619-6","article-title":"Characteristics and treatment results of recurrence in adult-type granulosa cell tumor of ovary","volume":"13","author":"Zhao","year":"2020","journal-title":"J Ovarian Res"},{"key":"2025082722464310000_17.7.e259788.2","article-title":"Granulosa cell tumor of the ovary: a retrospective study of 31 cases and a review of the literature","volume":"2018","author":"Dridi","year":"2018","journal-title":"Int J Surg Oncol"},{"key":"2025082722464310000_17.7.e259788.3","unstructured":"WHO Classification Of Tumours Editorial Board, International Agency For Research On Cancer . WHO classification of female genital tumours. Lyon International Agency For Research On Cancer, 2020."},{"key":"2025082722464310000_17.7.e259788.4","first-page":"135","article-title":"Granulosa cell tumor of ovary: a clinicopathological study of four cases with brief review of literature","volume":"5","author":"Vani","year":"2014","journal-title":"J Midlife Health"},{"key":"2025082722464310000_17.7.e259788.5","doi-asserted-by":"crossref","first-page":"2280","DOI":"10.1002\/cam4.1447","article-title":"Adjuvant chemotherapy in patients with operable granulosa cell tumors of the ovary: a surveillance, epidemiology, and end results cohort study","volume":"7","author":"Oseledchyk","year":"2018","journal-title":"Cancer Med"},{"key":"2025082722464310000_17.7.e259788.6","doi-asserted-by":"crossref","first-page":"iv1","DOI":"10.1093\/annonc\/mdy001","article-title":"Non-epithelial ovarian cancer: ESMO clinical practice guidelines for diagnosis, treatment and follow-up","volume":"29","author":"Ray-Coquard","year":"2018","journal-title":"Ann Oncol"},{"key":"2025082722464310000_17.7.e259788.7","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/s00428-022-03452-y","article-title":"Incidental FOXL2 mutated adult granulosa cell tumour of the ovary with thecoma-like foci","volume":"483","author":"Fischer","year":"2023","journal-title":"Virchows Arch"},{"key":"2025082722464310000_17.7.e259788.8","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1097\/PAS.0000000000001296","article-title":"Adult granulosa cell tumor with high-grade transformation: report of a series with FOXL2 mutation analysis","volume":"43","author":"Fashedemi","year":"2019","journal-title":"Am J Surg Pathol"},{"key":"2025082722464310000_17.7.e259788.9","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1097\/00004347-199410000-00003","article-title":"Luteinized adult granulosa cell tumors of the ovary: a report of four cases","volume":"13","author":"Young","year":"1994","journal-title":"Int J Gynecol Pathol"},{"key":"2025082722464310000_17.7.e259788.10","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199909000-00012"},{"key":"2025082722464310000_17.7.e259788.11","first-page":"124","article-title":"Adult granulosa cell tumor in a young woman: a case report and literature review","volume":"10","author":"Raivoherivony","year":"2020","journal-title":"OJ Pathol"},{"key":"2025082722464310000_17.7.e259788.12","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1097\/00004347-200007000-00011","article-title":"Androgenic adult granulosa cell tumor in a 13-year-old prepubertal patient: a case report and review of the literature","volume":"19","author":"Castro","year":"2000","journal-title":"Int J Gynecol Pathol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2024-259788","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T05:46:50Z","timestamp":1756360010000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2024-259788"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":12,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2024,7,16]]},"published-print":{"date-parts":[[2024,7]]}},"alternative-id":["10.1136\/bcr-2024-259788"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2024-259788","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2024,7]]}}}