{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:04:23Z","timestamp":1756425863617,"version":"3.44.0"},"reference-count":8,"publisher":"BMJ","issue":"8","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,8,13]]},"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:p>We present a case of atraumatic splenic rupture secondary to Epstein\u2013Barr virus (EBV) infection in a woman in her early 50s. The patient initially presented with sepsis secondary to pneumonia but then developed abdominal pain and distension. CT revealed splenic rupture with a significant perisplenic hematoma. Laboratory tests confirmed an EBV infection. Owing to frailty, she underwent fluoroscopy-guided splenic artery embolisation. This case highlights the rare risk of splenic rupture following EBV infection, even in the absence of typical symptoms of infectious mononucleosis.<\/jats:p>","DOI":"10.1136\/bcr-2024-259799","type":"journal-article","created":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T22:30:58Z","timestamp":1724970658000},"page":"e259799","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Atypical presentation of spontaneous splenic rupture secondary to Epstein\u2013Barr virus infection"],"prefix":"10.1136","volume":"17","author":[{"given":"Naveen","family":"Philip","sequence":"first","affiliation":[{"name":"Respiratory Medicine, Wrexham Maelor Hospital, Wrexham, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thoufeer","family":"Ali","sequence":"additional","affiliation":[{"name":"Respiratory Medicine, Wrexham Maelor Hospital, Wrexham, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Ashiqur","family":"Rahman","sequence":"additional","affiliation":[{"name":"Respiratory Medicine, Wrexham Maelor Hospital, Wrexham, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Cowell","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Wrexham Maelor Hospital, Wrexham, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,8,29]]},"reference":[{"key":"2025082804334498000_17.8.e259799.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2018.03.001"},{"key":"2025082804334498000_17.8.e259799.2","doi-asserted-by":"crossref","unstructured":"Aldrete JS . Spontaneous rupture of the spleen in patients with infectious mononucleosis. Mayo Clin Proc 1992;67. doi:10.1016\/s0025-619660835-0","DOI":"10.1016\/S0025-6196(12)60835-0"},{"key":"2025082804334498000_17.8.e259799.3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp1001116"},{"key":"2025082804334498000_17.8.e259799.4","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.injury.2015.10.071","article-title":"Splenic rupture in infectious mononucleosis: a systematic review of published case reports","volume":"47","author":"Bartlett","year":"2016","journal-title":"Injury"},{"key":"2025082804334498000_17.8.e259799.5","first-page":"175","article-title":"Spontaneous splenic rupture in infectious mononucleosis: a review","volume":"70","author":"Asgari","year":"1997","journal-title":"Yale J Biol Med"},{"key":"2025082804334498000_17.8.e259799.6","first-page":"449","article-title":"Splenomegaly in 2,505 patients at a large university medical center from 1913 to 1995:449 patients","volume":"169","author":"O\u2019Reilly","year":"1963","journal-title":"W J Med"},{"key":"2025082804334498000_17.8.e259799.7","unstructured":"Chapman J , Goyal A , Azevedo AM . Splenomegaly. In: StatPearls. Treasure Island (FL): StatPearls Publishing, 2023."},{"key":"2025082804334498000_17.8.e259799.8","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1080\/21645515.2017.1264797","article-title":"Recommended vaccinations for asplenic and hyposplenic adult patients","volume":"13","author":"Bonanni","year":"2017","journal-title":"Hum Vaccin Immunother"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2024-259799","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T11:33:52Z","timestamp":1756380832000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2024-259799"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":8,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2024,8,29]]},"published-print":{"date-parts":[[2024,8]]}},"alternative-id":["10.1136\/bcr-2024-259799"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2024-259799","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2024,8]]}}}