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Serological workup revealed highly positive cyclic citrullinated peptide (CCP) antibody (CCP-IgG\/anticitrullinated protein antibodies) and positive rheumatoid factor, serologies commonly associated with RA. The patient\u2019s symptoms responded very well to rituximab therapy.<\/jats:p>","DOI":"10.1136\/bcr-2024-259863","type":"journal-article","created":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T02:25:43Z","timestamp":1719368743000},"page":"e259863","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Case of isolated scleromalacia perforans with seropositivity for rheumatoid arthritis"],"prefix":"10.1136","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0442-062X","authenticated-orcid":false,"given":"Sama","family":"Hajizadeh","sequence":"first","affiliation":[{"name":"Internal Medicine, Allegheny Health Network, Pittsburgh, Pennsylvania, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Conor","family":"O'Donnell","sequence":"additional","affiliation":[{"name":"Allegheny Health Network, Pittsburgh, Pennsylvania, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam","family":"Dore","sequence":"additional","affiliation":[{"name":"Allegheny Health Network, Pittsburgh, Pennsylvania, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,6,25]]},"reference":[{"key":"2025082703474149000_17.6.e259863.1","first-page":"009","article-title":"Scleromalacia perforans\u2013 what we know and what we can do","volume":"S2","author":"Kopacz","year":"2013","journal-title":"J Clinic Experiment Ophthalmol"},{"key":"2025082703474149000_17.6.e259863.2","doi-asserted-by":"crossref","first-page":"163","DOI":"10.18240\/ijo.2020.01.23","article-title":"Molecular pathobiology of scleritis and its therapeutic implications","volume":"13","author":"Das","year":"2020","journal-title":"Int J Ophthalmol"},{"key":"2025082703474149000_17.6.e259863.3","doi-asserted-by":"crossref","unstructured":"Vitale AT , de la Maza MS . Scleral inflammatory disease. In: Retina. Elsevier, 2006: 1731\u201348. 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