{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:10:17Z","timestamp":1756372217959,"version":"3.44.0"},"reference-count":7,"publisher":"BMJ","issue":"10","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,9,18]]},"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:p>Mycosis fungoides (MF) is the most common type of cutaneous T-cell lymphoma in adults. However, it is rare in middle childhood. Such cases usually present with hypopigmented patches that may mimic common childhood dermatoses, thereby causing a delay in the diagnosis. Sezary syndrome is a rare and aggressive leukaemic variant of cutaneous lymphoma. We report a patient in middle childhood who presented with recurring non-specific folliculotropic manifestations. The final diagnosis of MF was arrived at after excluding all other possible dermatoses. Within a few months of skin manifestations, our index child was found to have blood involvement with similar clonal T-lymphoid cells. Such rapid development of Sezary syndrome within months of cutaneous presentation has never been described. There are no established treatment guidelines for the same in paediatric population. The patient underwent a matched sibling allogeneic transplant after a course of topical steroids and skin electron beam therapy.<\/jats:p>","DOI":"10.1136\/bcr-2024-259868","type":"journal-article","created":{"date-parts":[[2024,10,31]],"date-time":"2024-10-31T23:50:12Z","timestamp":1730418612000},"page":"e259868","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Folliculotropic mycosis fungoides with leukaemic involvement in middle childhood: a rare encounter"],"prefix":"10.1136","volume":"17","author":[{"given":"Preeti","family":"Tripathi","sequence":"first","affiliation":[{"name":"Pathology, Army Hospital Research and Referral, New Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niharika","family":"Mishra","sequence":"additional","affiliation":[{"name":"Pathology, Army Hospital Research and Referral, New Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4754-8340","authenticated-orcid":false,"given":"Sanjeev","family":"Khera","sequence":"additional","affiliation":[{"name":"Pediatrics, Army Hospital Research and Referral, New Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajiv","family":"Kumar","sequence":"additional","affiliation":[{"name":"Pathology, Army Hospital Research and Referral, New Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,10,31]]},"reference":[{"key":"2025082801513904000_17.10.e259868.1","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1111\/ijd.16385","article-title":"Response to 'Mycosis fungoides in pediatric population: comprehensive review on epidemiology, clinical presentation, and management.'","volume":"61","author":"Turkmen","year":"2022","journal-title":"Int J Dermatol"},{"key":"2025082801513904000_17.10.e259868.2","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1111\/ijd.16098","article-title":"Mycosis fungoides in pediatric population: comprehensive review on epidemiology, clinical presentation, and management","volume":"61","author":"Kothari","year":"2022","journal-title":"Int J Dermatol"},{"key":"2025082801513904000_17.10.e259868.3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2310\/7750.2009.08091","article-title":"Mycosis fungoides in the pediatric population: report from an international Childhood Registry of Cutaneous Lymphoma","volume":"14","author":"Pope","year":"2010","journal-title":"J Cutan Med Surg"},{"key":"2025082801513904000_17.10.e259868.4","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1016\/j.clindermatol.2016.07.010","article-title":"Cutaneous lymphoma: Kids are not just little people","volume":"34","author":"Ferenczi","year":"2016","journal-title":"Clin Dermatol"},{"key":"2025082801513904000_17.10.e259868.5","doi-asserted-by":"crossref","first-page":"4474","DOI":"10.1182\/bloodadvances.2020001627","article-title":"Nonmyeloablative allogeneic transplantation achieves clinical and molecular remission in cutaneous T-cell lymphoma","volume":"4","author":"Weng","year":"2020","journal-title":"Blood Adv"},{"key":"2025082801513904000_17.10.e259868.6","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2008.0033"},{"key":"2025082801513904000_17.10.e259868.7","doi-asserted-by":"crossref","unstructured":"Baykal C , Atc\u0131 T , Pehlivan Uluta\u015f G . Primary Cutaneous Lymphomas in Pediatric Age Group: Experience of a Single Dermatology Center. 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