{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T16:26:07Z","timestamp":1764433567789,"version":"3.44.0"},"reference-count":7,"publisher":"BMJ","issue":"6","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,5,21]]},"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:p>Steroid-induced acute pancreatitis is a rare form of pancreatitis that requires intensive care and has a high morbidity and mortality rate as there is no specific treatment. Management of steroid-induced pancreatitis is generally non-specific and supportive. Here, we are presenting a man in his 40s presented with epigastric pain, fever and vomiting. The patient was diagnosed case of rheumatoid arthritis, for which he was receiving regular 5\u2009mg oral prednisolone therapy. Based on history, and clinical, biochemical and radiological imaging a diagnosis of steroid-induced pancreatitis was made, which was successfully managed with the help of ulinastatin and other supportive treatments. A serine protease inhibitor like ulinastatin may be used early in the clinical management of steroid-induced pancreatitis.<\/jats:p>","DOI":"10.1136\/bcr-2024-260019","type":"journal-article","created":{"date-parts":[[2024,6,5]],"date-time":"2024-06-05T21:42:20Z","timestamp":1717623740000},"page":"e260019","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Role of ulinastatin in steroid-induced pancreatitis"],"prefix":"10.1136","volume":"17","author":[{"given":"Devarakonda","family":"Prithvi","sequence":"first","affiliation":[{"name":"Anaesthesiology and Critical Care, AIIMS, Patna, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9161-7000","authenticated-orcid":false,"given":"Neeraj","family":"Kumar","sequence":"additional","affiliation":[{"name":"Anaesthesiology and Critical Care, AIIMS, Patna, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ajeet","family":"Kumar","sequence":"additional","affiliation":[{"name":"Anaesthesiology and Critical Care, AIIMS, Patna, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abhyuday","family":"Kumar","sequence":"additional","affiliation":[{"name":"Anaesthesiology and Critical Care, AIIMS, Patna, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,6,5]]},"reference":[{"doi-asserted-by":"publisher","key":"2025082708055116000_17.6.e260019.1","DOI":"10.2165\/00002018-200831100-00002"},{"key":"2025082708055116000_17.6.e260019.2","article-title":"Steroid-induced Pancreatitis: establishing an accurate Association poses a challenge","volume":"12","author":"Minupuri","year":"2020","journal-title":"Cureus"},{"doi-asserted-by":"publisher","key":"2025082708055116000_17.6.e260019.3","DOI":"10.1136\/gut.2006.115246"},{"key":"2025082708055116000_17.6.e260019.4","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1089\/gtmb.2015.0192","article-title":"A meta-analysis on the effect of Ulinastatin on serum levels of C-reactive protein, interleukin 6, and tumor necrosis factor alpha in Asian patients with acute Pancreatitis","volume":"20","author":"Zhang","year":"2016","journal-title":"Genetic Testing and Molecular Biomarkers"},{"key":"2025082708055116000_17.6.e260019.5","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.jcrc.2018.01.021","article-title":"Role of Ulinastatin, a Trypsin inhibitor, in severe acute Pancreatitis in critical care setting: A retrospective analysis","volume":"45","author":"Lagoo","year":"2018","journal-title":"J Crit Care"},{"key":"2025082708055116000_17.6.e260019.6","first-page":"488","article-title":"Action of Antiproteases on the inflammatory response in acute Pancreatitis","volume":"8","author":"Chen","year":"2007","journal-title":"JOP"},{"key":"2025082708055116000_17.6.e260019.7","first-page":"535","article-title":"Efficacy and safety of intravenous Ulinastatin versus placebo along with standard supportive care in subjects with mild or severe acute Pancreatitis","volume":"61","author":"Abraham","year":"2013","journal-title":"J Assoc Physicians India"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2024-260019","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T15:05:58Z","timestamp":1756307158000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2024-260019"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":7,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2024,6,5]]},"published-print":{"date-parts":[[2024,6]]}},"alternative-id":["10.1136\/bcr-2024-260019"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2024-260019","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2024,6]]}}}