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Here, we present a patient with RA undergoing evaluation for neutropenia and splenomegaly who was later diagnosed with T-LGL leukaemia.<\/jats:p>","DOI":"10.1136\/bcr-2024-260470","type":"journal-article","created":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T12:07:32Z","timestamp":1725019652000},"page":"e260470","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["T-cell large granular lymphocytic leukaemia in rheumatoid arthritis"],"prefix":"10.1136","volume":"17","author":[{"given":"Indira","family":"Acharya","sequence":"first","affiliation":[{"name":"Internal Medicine, MedStar Union Memorial Hospital, Baltimore, Maryland, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lauren N","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Georgetown University School of Medicine, Washington, District of Columbia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bhaskar V","family":"Kallakury","sequence":"additional","affiliation":[{"name":"Department of Pathology, MedStar Georgetown University Hospital, Washington DC, District of Columbia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Haas","sequence":"additional","affiliation":[{"name":"Internal Medicine, MedStar Harbor Hospital, Baltimore, Maryland, USA"},{"name":"MedStar Franklin Square Medical Center, Baltimore, Maryland, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,8,30]]},"reference":[{"key":"2025082803335618000_17.8.e260470.1","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/s00296-020-04757-4","article-title":"Analysis of a single-institution cohort of patients with Felty\u2019s syndrome and T-cell large granular lymphocytic leukemia in the setting of rheumatoid arthritis","volume":"41","author":"Gorodetskiy","year":"2021","journal-title":"Rheumatol Int"},{"key":"2025082803335618000_17.8.e260470.2","doi-asserted-by":"crossref","DOI":"10.3390\/cancers13174418","article-title":"Large Granular Lymphocytic Leukemia: From Immunopathogenesis to Treatment of Refractory Disease","volume":"13","author":"Zawit","year":"2021","journal-title":"Cancers (Basel)"},{"key":"2025082803335618000_17.8.e260470.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2004.05.002"},{"key":"2025082803335618000_17.8.e260470.4","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2022.869205","article-title":"Intersection Between Large Granular Lymphocyte Leukemia and Rheumatoid Arthritis","volume":"12","author":"Moosic","year":"2022","journal-title":"Front Oncol"},{"key":"2025082803335618000_17.8.e260470.5","doi-asserted-by":"crossref","DOI":"10.1177\/2324709620941303","article-title":"T-Cell Large Granular Lymphocyte Leukemia in a Patient With Rheumatoid Arthritis","volume":"8","author":"Naji Rad","year":"2020","journal-title":"J Investig Med High Impact Case Rep"},{"key":"2025082803335618000_17.8.e260470.6","doi-asserted-by":"crossref","DOI":"10.1097\/MOH.0b013e32834760fb","article-title":"The spectrum of LGL and Felty\u2019s Syndrome","volume":"18","author":"Liu","year":"2011","journal-title":"Curr Opin Hematol"},{"key":"2025082803335618000_17.8.e260470.7","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2016.68"},{"key":"2025082803335618000_17.8.e260470.8","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780400406"},{"key":"2025082803335618000_17.8.e260470.9","doi-asserted-by":"crossref","first-page":"1914","DOI":"10.1002\/art.40654","article-title":"Prevalence and Characteristics of Persistent Clonal T Cell Large Granular Lymphocyte Expansions in Rheumatoid Arthritis","volume":"70","author":"Schwaneck","year":"2018","journal-title":"Arthritis Rheumatol"},{"key":"2025082803335618000_17.8.e260470.10","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.clim.2009.03.515","article-title":"T cell large granular lymphocyte leukemia associated with rheumatoid arthritis and neutropenia","volume":"132","author":"Shah","year":"2009","journal-title":"Clin Immunol"},{"key":"2025082803335618000_17.8.e260470.11","doi-asserted-by":"publisher","DOI":"10.1016\/j.lpm.2014.02.007"},{"key":"2025082803335618000_17.8.e260470.12","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2006.01.003"},{"key":"2025082803335618000_17.8.e260470.13","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-11-3951"},{"key":"2025082803335618000_17.8.e260470.14","doi-asserted-by":"crossref","first-page":"5795","DOI":"10.1182\/blood-2022-163663","article-title":"Intense Immunosuppressive Therapy (anti-thymocyte globulin, alemtuzumab) As Salvage Therapy in Refractory T-Cell Large Granular Lymphocytic Leukemia and Pure Red Cell Aplasia","volume":"140","author":"Ullah","year":"2022","journal-title":"Blood"},{"key":"2025082803335618000_17.8.e260470.15","doi-asserted-by":"crossref","unstructured":"Dearden CE . 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