{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T09:23:43Z","timestamp":1768641823779,"version":"3.49.0"},"reference-count":30,"publisher":"BMJ","issue":"9","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,8,20]]},"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:p>It is highly uncommon for solid tumours to metastasise to the testis. Here, we report a case of metachronous testicular metastasis from clear cell renal cell cancer (RCC) in a male patient 3 years after left radical nephrectomy. Ultrasound of the scrotum showed a 3.5 cm \u00d7 4\u2009cm left testicular mass with normal serum tumour markers. The patient underwent left high inguinal orchidectomy, which revealed metastatic renal cell carcinoma. CT of the chest, abdomen and pelvis showed multiple liver secondaries. Cabozantinib was started for metastatic RCC, and the patient showed no evidence of disease progression in a follow-up of 1 year.<\/jats:p>","DOI":"10.1136\/bcr-2024-260647","type":"journal-article","created":{"date-parts":[[2024,9,4]],"date-time":"2024-09-04T01:00:53Z","timestamp":1725411653000},"page":"e260647","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Post nephrectomy metachronous testicular metastasis in a case of clear cell renal cell carcinoma (ccRCC)"],"prefix":"10.1136","volume":"17","author":[{"given":"Rudra Prasad","family":"Ghorai","sequence":"first","affiliation":[{"name":"Department of Urology, All India Institute of Medical Sciences (AIIMS), New Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjay","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Urology, All India Institute of Medical Sciences (AIIMS), New Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6820-3304","authenticated-orcid":false,"given":"Vaibhav","family":"Aggarwal","sequence":"additional","affiliation":[{"name":"Department of Urology, All India Institute of Medical Sciences (AIIMS), New Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seema","family":"Kaushal","sequence":"additional","affiliation":[{"name":"Department of Pathology, All India Institute of Medical Sciences (AIIMS), New Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,9,3]]},"reference":[{"key":"2025082803213419000_17.9.e260647.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2007.12.001"},{"key":"2025082803213419000_17.9.e260647.2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2559.2000.00983.x"},{"key":"2025082803213419000_17.9.e260647.3","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-004-0466-0"},{"key":"2025082803213419000_17.9.e260647.4","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/S0022-5347(17)69962-2","article-title":"Solitary testicular metastasis simulating primary tumor and antedating clinical hypernephroma of the kidney; report of a case","volume":"55","author":"BANDLER","year":"1946","journal-title":"J Urol"},{"key":"2025082803213419000_17.9.e260647.5","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181788516"},{"key":"2025082803213419000_17.9.e260647.6","doi-asserted-by":"crossref","first-page":"16","DOI":"10.29245\/2572-9411\/2019\/2.1177","article-title":"Metastatic Carcinoma to the Testis - A Mini Review","volume":"4","author":"Wang","year":"2019","journal-title":"J Rare Dis Res Treat"},{"key":"2025082803213419000_17.9.e260647.7","article-title":"Metastatic Renal Cell Carcinoma to the Testis: A Clinicopathologic Analysis of Five Cases","volume":"2020","author":"Wang","year":"2020","journal-title":"Case Rep Pathol"},{"key":"2025082803213419000_17.9.e260647.8","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197208)30:2<481::AID-CNCR2820300228>3.0.CO;2-X"},{"key":"2025082803213419000_17.9.e260647.9","article-title":"Unusual Ultrasound Presentation of Testicular Metastasis from Renal Clear Cell Carcinoma","volume":"8","author":"Dell\u2019Atti","year":"2016","journal-title":"Rare Tumors"},{"key":"2025082803213419000_17.9.e260647.10","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1177\/2051415815607420","article-title":"Metachronous bilateral testicular metastases from renal cell carcinoma: a case report","volume":"10","author":"Reekhaye","year":"2017","journal-title":"J Clin Urol"},{"key":"2025082803213419000_17.9.e260647.11","doi-asserted-by":"publisher","DOI":"10.1080\/003655999750016168"},{"key":"2025082803213419000_17.9.e260647.12","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.3892\/ol.2014.1830","article-title":"Simultaneous bilateral testicular metastases from renal clear cell carcinoma: A case report and review of the literature","volume":"7","author":"Moriyama","year":"2014","journal-title":"Oncol Lett"},{"key":"2025082803213419000_17.9.e260647.13","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1159\/000473457","article-title":"Intrascrotal metastasis of renal cell carcinoma. 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