{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T23:01:41Z","timestamp":1793142101901,"version":"4.5.0"},"reference-count":9,"publisher":"BMJ","issue":"8","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,8,3]]},"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:p>Ayahuasca is a plant-based psychoactive decoction, traditionally used by indigenous Amazonian peoples, which commonly contains the hallucinogen N,N-dimethyltryptamine (DMT). There is now growing interest across the Western world in psychedelics including Ayahuasca.<\/jats:p>\n               <jats:p>This case describes a previously well male with no risk factors for adverse psychiatric outcomes or forensic history. Following controlled Ayahuasca use, he developed an enduring psychotic episode, during which he significantly assaulted a relative and was admitted to a forensic psychiatric unit. He was treated with the antipsychotic aripiprazole, and his psychotic symptoms abated. 18 months following his admission, recovery has been sustained.<\/jats:p>\n               <jats:p>Previous case reports have described psychosis following Ayahuasca ingestion, but typically of short duration in patients with a personal or family history of psychiatric illness, or in those taking other substances. With the growing use of Ayahuasca, it is important to highlight that adverse effects may include more prolonged psychotic symptoms and the risk of psychotically mediated violence.<\/jats:p>","DOI":"10.1136\/bcr-2024-260648","type":"journal-article","created":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T21:25:15Z","timestamp":1723670715000},"page":"e260648","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Drug-induced psychosis following use of Ayahuasca: a presentation to forensic psychiatric services"],"prefix":"10.1136","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-9147-4608","authenticated-orcid":false,"given":"Morven Rosemary","family":"Baker","sequence":"first","affiliation":[{"name":"Royal Edinburgh Hospital, Edinburgh, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher Iain","family":"O'Shea","sequence":"additional","affiliation":[{"name":"Royal Edinburgh Hospital, Edinburgh, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2024,8,14]]},"reference":[{"key":"2025082801135544000_17.8.e260648.1","doi-asserted-by":"crossref","first-page":"12307","DOI":"10.1021\/acsomega.2c00795","article-title":"New insights into the chemical composition of ayahuasca","volume":"7","author":"Rodr\u00edguez","year":"2022","journal-title":"ACS Omega"},{"key":"2025082801135544000_17.8.e260648.2","doi-asserted-by":"crossref","DOI":"10.3390\/ph13110334","article-title":"Toxicokinetics and toxicodynamics of ayahuasca alkaloids N,N-dimethyltryptamine (DMT), harmine, harmaline and tetrahydroharmine: clinical and forensic impact","volume":"13","author":"Brito-da-Costa","year":"2020","journal-title":"Pharmaceuticals (Basel)"},{"key":"2025082801135544000_17.8.e260648.3","doi-asserted-by":"crossref","DOI":"10.1002\/hup.2835","article-title":"N,N-dimethyltryptamine and Amazonian ayahuasca plant medicine","volume":"37","author":"James","year":"2022","journal-title":"Hum Psychopharmacol"},{"key":"2025082801135544000_17.8.e260648.4","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgph.0000438","article-title":"Adverse effects of ayahuasca: results from the global ayahuasca survey","volume":"2","author":"Bouso","year":"2022","journal-title":"PLOS Glob Public Health"},{"key":"2025082801135544000_17.8.e260648.5","doi-asserted-by":"publisher","DOI":"10.1590\/1516-4446-2015-1701"},{"key":"2025082801135544000_17.8.e260648.6","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291718001356"},{"key":"2025082801135544000_17.8.e260648.7","doi-asserted-by":"publisher","DOI":"10.1177\/2045125316689030"},{"key":"2025082801135544000_17.8.e260648.8","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.rcp.2019.10.005","article-title":"Psychosis induced by abuse of ayahuasca: a case report","volume":"50","author":"Palma-\u00c1lvarez","year":"2021","journal-title":"Rev Colomb Psiquiatr"},{"key":"2025082801135544000_17.8.e260648.9","first-page":"236","article-title":"Ayahuasca-induced psychosis: a case report","volume":"51","author":"Tapia","year":"2022","journal-title":"Rev Colomb Psiquiatr"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2024-260648","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T08:14:01Z","timestamp":1756368841000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2024-260648"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":9,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2024,8,14]]},"published-print":{"date-parts":[[2024,8]]}},"alternative-id":["10.1136\/bcr-2024-260648"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2024-260648","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8]]}}}