{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T06:59:13Z","timestamp":1764053953695,"version":"3.44.0"},"reference-count":18,"publisher":"BMJ","issue":"3","license":[{"start":{"date-parts":[[2025,3,25]],"date-time":"2025-03-25T00:00:00Z","timestamp":1742860800000},"content-version":"unspecified","delay-in-days":24,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2025,3,15]]},"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:p>Primary cutaneous adenoid cystic carcinoma (PCACC) is a rare adnexal tumour of the skin, predominantly affecting individuals over 50 years of age, with no established gender predilection. It can arise on various anatomical sites without a clear preference. To date, fewer than 200 cases have been documented in the literature.<\/jats:p>\n               <jats:p>We present a case of a young, otherwise healthy female who developed a slow-growing painless, skin-coloured scalp nodule. Histopathological examination of an excisional biopsy revealed a dermal tumour composed of basaloid cells arranged in a characteristic cribriform pattern. A thorough diagnostic workup, including sonographic imaging, immunohistochemical analysis and multidisciplinary team discussions, ultimately confirmed the diagnosis of PCACC. This case underscores the diagnostic and therapeutic challenges associated with PCACC.<\/jats:p>","DOI":"10.1136\/bcr-2024-260654","type":"journal-article","created":{"date-parts":[[2025,3,26]],"date-time":"2025-03-26T02:13:35Z","timestamp":1742955215000},"page":"e260654","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Primary cutaneous adenoid cystic carcinoma arising in the scalp: a diagnostic challenge"],"prefix":"10.1136","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-8786-5246","authenticated-orcid":false,"given":"Jonathan","family":"Mokhtar","sequence":"first","affiliation":[{"name":"College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, UAE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4741-4377","authenticated-orcid":false,"given":"Fatemeh","family":"Akbarpoor","sequence":"additional","affiliation":[{"name":"College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, UAE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neshteman Gorgees","family":"Oghanna","sequence":"additional","affiliation":[{"name":"College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, UAE"},{"name":"Pathology and Laboratory Medicine, Mediclinic City Hospital, Dubai, UAE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas John","family":"Bennett","sequence":"additional","affiliation":[{"name":"College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, UAE"},{"name":"Plastic and Reconstructive Surgery, Mediclinic City Hospital, Dubai, UAE"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,3,25]]},"reference":[{"key":"2025082722400975000_18.3.e260654.1","doi-asserted-by":"crossref","first-page":"9505","DOI":"10.4081\/dr.2022.9505","article-title":"Primary cutaneous adenoid cystic carcinoma of the scalp: dermatosurgical approach with favourable outcome","volume":"14","author":"Tchernev","year":"2022","journal-title":"Dermatol Reports"},{"key":"2025082722400975000_18.3.e260654.2","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/j.radcr.2023.10.071","article-title":"Primary cutaneous adenoid cystic carcinoma with lung metastasis: A case report with literature review","volume":"19","author":"El Mansoury","year":"2024","journal-title":"Radiol Case Rep"},{"key":"2025082722400975000_18.3.e260654.3","first-page":"1016","article-title":"Primary cutaneous adenoid cystic carcinoma mimicking dermal cylindroma: histology of the complete surgical excision as the key to diagnosis","volume":"16","author":"R\u00fctten","year":"2018","journal-title":"J Deutsche Derma Gesell"},{"key":"2025082722400975000_18.3.e260654.4","doi-asserted-by":"crossref","unstructured":"Costa REAR da , Oliveira FTR de , Coutinho Neto E de S , et al . 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A clinical, histological, and immunocytochemical comparison with adenoid cystic carcinoma of salivary glands and adenoid basal cell carcinoma","volume":"8","author":"Wick","year":"1986","journal-title":"Am J Dermatopathol"},{"key":"2025082722400975000_18.3.e260654.9","doi-asserted-by":"crossref","first-page":"2374289521998030","DOI":"10.1177\/2374289521998030","article-title":"Educational Case: Basal Cell Carcinoma","volume":"8","author":"O\u2019Connell","year":"2021","journal-title":"Acad Pathol"},{"key":"2025082722400975000_18.3.e260654.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2007.12.005"},{"key":"2025082722400975000_18.3.e260654.11","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1097\/00000372-199812000-00005","article-title":"Primary cutaneous adenoid cystic carcinoma with lymph node metastasis","volume":"20","author":"Kato","year":"1998","journal-title":"Am J Dermatopathol"},{"key":"2025082722400975000_18.3.e260654.12","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1097\/PAS.0000000000000463","article-title":"Detection of MYB Alterations and Other Immunohistochemical Markers in Primary Cutaneous Adenoid Cystic Carcinoma","volume":"39","author":"North","year":"2015","journal-title":"Am J Surg Pathol"},{"key":"2025082722400975000_18.3.e260654.13","doi-asserted-by":"crossref","first-page":"100098","DOI":"10.1016\/j.acpath.2023.100098","article-title":"Educational Case: An invasive salivary gland tumor: Adenoid cystic carcinoma of the parotid gland","volume":"10","author":"Eberle-Singh","year":"2023","journal-title":"Acad Pathol"},{"key":"2025082722400975000_18.3.e260654.14","doi-asserted-by":"crossref","first-page":"244","DOI":"10.4103\/0019-5154.110874","article-title":"Adenoid basal cell carcinoma and its mimics","volume":"58","author":"Jetley","year":"2013","journal-title":"Indian J Dermatol"},{"key":"2025082722400975000_18.3.e260654.15","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hym119"},{"key":"2025082722400975000_18.3.e260654.16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2020.07.113"},{"key":"2025082722400975000_18.3.e260654.17","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1097\/SCS.0000000000008300","article-title":"Use of the O-Z Flap to Repair Scalp Defects After Cancer Tumor Resection","volume":"33","author":"Lin","year":"2022","journal-title":"J Craniofac Surg"},{"key":"2025082722400975000_18.3.e260654.18","doi-asserted-by":"crossref","unstructured":"Fernandes RP , Pirgousis P . Local\/regional flaps in oral\/head and neck reconstruction. In: Kuriakose MA , ed. Contemporary oral oncology. 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