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Lifelong anticoagulation was commenced; the patient was initially observed and then started on sirolimus at disease progression. We describe the first published case of EHE presenting with DVT in a child. Clinicians need to be mindful of the association between cancer and thrombosis, even in paediatric patients.<\/jats:p>","DOI":"10.1136\/bcr-2024-260711","type":"journal-article","created":{"date-parts":[[2024,12,4]],"date-time":"2024-12-04T20:35:24Z","timestamp":1733344524000},"page":"e260711","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Advanced epithelioid haemangioendothelioma in a child presenting as deep vein thrombosis"],"prefix":"10.1136","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-7240-9470","authenticated-orcid":false,"given":"Timothy","family":"Shields","sequence":"first","affiliation":[{"name":"Paediatrics, Kingston Hospital NHS Foundation Trust, Kingston upon Thames, UK"},{"name":"Paediatrics, King's College Hospital NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erika","family":"Pace","sequence":"additional","affiliation":[{"name":"Department of Radiology, Royal Marsden Hospital NHS Trust, London, UK"},{"name":"The Institute of Cancer Research, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sue","family":"Height","sequence":"additional","affiliation":[{"name":"Paediatric Haematology, King's College Hospital NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola","family":"Angelini","sequence":"additional","affiliation":[{"name":"Paediatric Haemato-Oncology, Royal Marsden Hospital NHS Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,12,4]]},"reference":[{"key":"2025082708445100000_17.12.e260711.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2011.03.052"},{"key":"2025082708445100000_17.12.e260711.2","doi-asserted-by":"publisher","DOI":"10.1067\/mpd.2001.118192"},{"key":"2025082708445100000_17.12.e260711.3","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1182\/blood.V83.5.1251.1251","article-title":"Venous thromboembolic complications (VTE) in children: first analyses of the Canadian Registry of VTE","volume":"83","author":"Andrew","year":"1994","journal-title":"Blood"},{"key":"2025082708445100000_17.12.e260711.4","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1111\/bjh.18239","article-title":"Thrombophilia testing: A British Society for Haematology guideline","volume":"198","author":"Arachchillage","year":"2022","journal-title":"Br J Haematol"},{"key":"2025082708445100000_17.12.e260711.5","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-10-053736"},{"key":"2025082708445100000_17.12.e260711.6","doi-asserted-by":"publisher","DOI":"10.3978\/j.issn.2078-6891.2011.021"},{"key":"2025082708445100000_17.12.e260711.7","unstructured":"National Institute for Health and Care Excellence . 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