{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T14:24:41Z","timestamp":1762957481509,"version":"3.44.0"},"reference-count":16,"publisher":"BMJ","issue":"9","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,8,28]]},"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:p>Neurocysticercosis (NCC) is the most common parasitic infection of the central nervous system, caused by the pork tapeworm, <jats:italic>Taenia solium<\/jats:italic>. Common presenting features are seizures, headaches and focal neurodeficits. The present report details the anecdote of a middle-aged Asian man, who presented with subacute onset of persistent nausea, vomiting and hiccups. Following unsuccessful trials with numerous prokinetic, antipsychotic, muscle relaxant and anticonvulsant medications, as well as an uneventful battery of gastrointestinal tests, he was referred for neurological evaluation. The constellation of symptoms was congruent with the diagnosis of area postrema syndrome. Although initial CT scan of brain was normal, MRI with contrast evaluation revealed a circumscribed, ring-enhancing lesion of the dorsal medulla oblongata, reminiscent of colloid vesicular stage of NCC. The patient was successfully treated with steroids and albendazole. The association of refractory singultus, nausea and vomiting and NCC is thus far, not reported in the literature.<\/jats:p>","DOI":"10.1136\/bcr-2024-260797","type":"journal-article","created":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T14:56:49Z","timestamp":1726153009000},"page":"e260797","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Refractory singultus and area postrema syndrome as a presentation of neurocysticercosis"],"prefix":"10.1136","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6232-0921","authenticated-orcid":false,"given":"Amlan Kusum","family":"Datta","sequence":"first","affiliation":[{"name":"Neurology, Narayana Multispeciality Hospital, Barasat, West Bengal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sudeshna","family":"Malakar","sequence":"additional","affiliation":[{"name":"Apollo Gleneagles Hospital, Kolkata, West Bengal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8963-3554","authenticated-orcid":false,"given":"Adreesh","family":"Mukherjee","sequence":"additional","affiliation":[{"name":"Neurology, Bangur Institute of Neurosciences, Institute of Post Graduate Medical Education and Research, Kolkata, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,9,12]]},"reference":[{"key":"2025082713072143000_17.9.e260797.1","first-page":"182","article-title":"The area postrema: a brain monitor and integrator of systemic autonomic state","volume":"14","author":"Price","year":"2008","journal-title":"Neurosci"},{"key":"2025082713072143000_17.9.e260797.2","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.neuron.2020.11.010","article-title":"Area Postrema Cell Types that Mediate Nausea-Associated Behaviors","volume":"109","author":"Zhang","year":"2021","journal-title":"Neuron"},{"key":"2025082713072143000_17.9.e260797.3","doi-asserted-by":"publisher","DOI":"10.1177\/1352458518813105"},{"key":"2025082713072143000_17.9.e260797.4","first-page":"e1642","article-title":"Area postrema syndrome: frequency, criteria, and severity in AQP4-IgG-positive NMOSD","volume":"91","author":"Shosha","year":"2018","journal-title":"Neurol (ECronicon)"},{"key":"2025082713072143000_17.9.e260797.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ncl.2018.07.003"},{"key":"2025082713072143000_17.9.e260797.6","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0005153","article-title":"Systematic review and meta-analysis estimating association of cysticercosis and neurocysticercosis with epilepsy","volume":"11","author":"Debacq","year":"2017","journal-title":"PLoS Negl Trop Dis"},{"key":"2025082713072143000_17.9.e260797.7","doi-asserted-by":"publisher","DOI":"10.1097\/00004728-198811000-00004"},{"key":"2025082713072143000_17.9.e260797.8","doi-asserted-by":"publisher","DOI":"10.1002\/ana.22121"},{"key":"2025082713072143000_17.9.e260797.9","first-page":"1479","article-title":"Intractable hiccup and nausea with periaqueductal lesions in neuromyelitis optica","volume":"65","author":"Misu","year":"2005","journal-title":"Neurol (ECronicon)"},{"key":"2025082713072143000_17.9.e260797.10","doi-asserted-by":"crossref","DOI":"10.1007\/s11910-018-0856-0","article-title":"Intractable Hiccups","volume":"18","author":"Rouse","year":"2018","journal-title":"Curr Neurol Neurosci Rep"},{"key":"2025082713072143000_17.9.e260797.11","doi-asserted-by":"crossref","DOI":"10.1186\/s40064-016-3034-3","article-title":"Neurotransmitters in hiccups","volume":"5","author":"Nausheen","year":"2016","journal-title":"Springerplus"},{"key":"2025082713072143000_17.9.e260797.12","doi-asserted-by":"crossref","unstructured":"Shankar B , Narayanan R , Paruthikunnan SM . 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