{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T04:20:07Z","timestamp":1783743607101,"version":"3.55.0"},"reference-count":5,"publisher":"BMJ","issue":"11","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,11,6]]},"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:p>A woman in her late 60s presented with widespread, itchy, dark lesions over her trunk and legs for 1\u2009month. Initially, she was managed as nutritional dermatitis and experienced partial improvement. However, her condition worsened over 2\u2009months, characterised by aggravated skin lesions, new-onset diabetes and a 12\u2009kg weight loss. On suspicion of necrolytic migratory erythema (NME) secondary to glucagonoma, the contrast-enhanced CT (CECT) abdomen revealed a primary pancreatic lesion with multiple liver metastases. The diagnosis of neuroendocrine tumour was confirmed by liver biopsy with immunohistochemistry, and stage 4 status was revealed by fluorodeoxyglucose-positron emission tomography CT. Following 6-monthly octreotide injections and nutritional and supportive care, her skin lesions completely resolved. This case emphasises the significance of recognising NME, a rare and often misdiagnosed dermatological condition, as it may signify an underlying occult neuroendocrine pancreatic malignancy. Early recognition is crucial for the timely initiation of appropriate management.<\/jats:p>","DOI":"10.1136\/bcr-2024-260893","type":"journal-article","created":{"date-parts":[[2024,11,28]],"date-time":"2024-11-28T04:05:43Z","timestamp":1732766743000},"page":"e260893","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Necrolytic migratory erythema: a fortuitous diagnosis"],"prefix":"10.1136","volume":"17","author":[{"given":"Amuthavalli","family":"Kanagarajan","sequence":"first","affiliation":[{"name":"Dermatology, PSG Institute of Medical Sciences and Research, Coimbatore, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daya","family":"Babu","sequence":"additional","affiliation":[{"name":"Dermatology, PSG Institute of Medical Sciences and Research, Coimbatore, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanmugasekar","family":"Chandrasekaran","sequence":"additional","affiliation":[{"name":"Dermatology, PSG Institute of Medical Sciences and Research, Coimbatore, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2024,11,27]]},"reference":[{"key":"2025082800552777000_17.11.e260893.1","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2017.7703"},{"key":"2025082800552777000_17.11.e260893.2","doi-asserted-by":"crossref","DOI":"10.3390\/jcm12155138","article-title":"A Comprehensive Review on Neuroendocrine Neoplasms: Presentation, Pathophysiology and Management","volume":"12","author":"Sultana","year":"2023","journal-title":"J Clin Med"},{"key":"2025082800552777000_17.11.e260893.3","doi-asserted-by":"publisher","DOI":"10.1590\/S0365-05962013000100001"},{"key":"2025082800552777000_17.11.e260893.4","unstructured":"Foss MG , Hashmi MF , Ferrer-Bruker SJ . Necrolytic migratory erythema.2023. Available: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK532872\/"},{"key":"2025082800552777000_17.11.e260893.5","doi-asserted-by":"crossref","first-page":"49","DOI":"10.4103\/ijdvl.IJDVL_588_18","article-title":"Glucagonoma syndrome with atypical necrolytic migratory erythema","volume":"87","author":"He","year":"2021","journal-title":"IJDVL"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2024-260893","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T07:55:33Z","timestamp":1756367733000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2024-260893"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":5,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2024,11,27]]},"published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1136\/bcr-2024-260893"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2024-260893","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11]]}}}