{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T19:18:19Z","timestamp":1782242299318,"version":"3.54.5"},"reference-count":5,"publisher":"BMJ","issue":"2","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,11,21]]},"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:p>Non-typhoidal <jats:italic>Salmonella<\/jats:italic> (NTS) infections, though commonly associated with gastroenteritis, can demonstrate focal non-gastrointestinal organ involvement. We present the case of a mid-30s woman who presented with long-standing left flank pain and was subsequently diagnosed with refractory <jats:italic>Salmonella<\/jats:italic> pyelonephritis in the setting of nephrolithiasis, severe hydronephrosis and parenchymal thinning suggestive of renal atrophy despite normal serum creatinine and a normal appearing contralateral kidney. Despite several guideline-based antibiotic courses, we failed to clear her multidrug-resistant <jats:italic>Salmonella<\/jats:italic> species bacteriuria. We then established percutaneous nephrostomy (PCN) drainage but still were unable to clear her infection, and it was noted PCN output dropped below 30\u2009cc per day suggesting a non-functional renal unit.<\/jats:p>\n               <jats:p>This patient was successfully managed with minimally invasive laparoscopic robotic-assisted left nephrectomy which finally cleared her bacteriuria. This case illustrates challenges in the management of refractory atypical <jats:italic>Salmonella<\/jats:italic> infections and highlights the rare indication of nephrectomy in such cases.<\/jats:p>","DOI":"10.1136\/bcr-2024-260911","type":"journal-article","created":{"date-parts":[[2025,2,3]],"date-time":"2025-02-03T09:35:16Z","timestamp":1738575316000},"page":"e260911","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Refractory <i>Salmonella<\/i> infection resulting in nephrectomy"],"prefix":"10.1136","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5076-4178","authenticated-orcid":false,"given":"Dillon Jay","family":"Patel","sequence":"first","affiliation":[{"name":"School of Medicine, New York Medical College, Valhalla, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0897-9220","authenticated-orcid":false,"given":"Evan","family":"Spencer","sequence":"additional","affiliation":[{"name":"WMCHealth, Valhalla, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerald","family":"Matthews","sequence":"additional","affiliation":[{"name":"WMCHealth, Valhalla, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sameh","family":"Naim","sequence":"additional","affiliation":[{"name":"Urology, NYC Health + Hospitals Metropolitan, New York, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2025,2,3]]},"reference":[{"key":"2025082702404107000_18.2.e260911.1","doi-asserted-by":"crossref","first-page":"100071","DOI":"10.1016\/j.jfp.2023.100071","article-title":"Salmonella Outbreaks Linked to Beef, United States, 2012-2019","volume":"86","author":"Canning","year":"2023","journal-title":"J Food Prot"},{"key":"2025082702404107000_18.2.e260911.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2006.05.007"},{"key":"2025082702404107000_18.2.e260911.3","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/23.2.388"},{"key":"2025082702404107000_18.2.e260911.4","doi-asserted-by":"crossref","first-page":"205","DOI":"10.3390\/idr13010023","article-title":"A Case-Control Study on the Association between Salmonella Bacteriuria and Cystoscopy","volume":"13","author":"Yeung","year":"2021","journal-title":"Infect Dis Rep"},{"key":"2025082702404107000_18.2.e260911.5","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-006-0162-x"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2024-260911","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T09:40:46Z","timestamp":1756287646000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2024-260911"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":5,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025,2,3]]},"published-print":{"date-parts":[[2025,2]]}},"alternative-id":["10.1136\/bcr-2024-260911"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2024-260911","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2]]}}}