{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T11:45:58Z","timestamp":1793965558656,"version":"4.8.0"},"reference-count":11,"publisher":"BMJ","issue":"10","license":[{"start":{"date-parts":[[2024,10,25]],"date-time":"2024-10-25T00:00:00Z","timestamp":1729814400000},"content-version":"unspecified","delay-in-days":24,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,10,4]]},"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:p>A man in his mid-20s presented to the occupational health service following an ocular projection with a concentrated solution of lymphocytic choriomeningitis virus (LCMV clone-13). Subsequently, a regular clinical and biological follow-up was initiated. 7 days after exposure, the patient developed influenza-like symptoms. During the acute phase, specific RT-PCR testing of blood plasma was negative for LCMV. Symptomatic treatment was administered, and the symptoms resolved after a few days. The patient remained asymptomatic in the following weeks. Serological follow-up detected a seroconversion 6 weeks after exposure, indicating a recent infection. The occupational health service\u2019s protocol, comprising clinical monitoring and serological surveillance, facilitated the detection of seroconversion. This case underscores ocular mucosal exposure as a route of occupational LCMV transmission, which is often not considered. It served as an opportunity to review and enhance prevention measures and laboratory protocols within the biosafety level P2 facility.<\/jats:p>","DOI":"10.1136\/bcr-2024-260966","type":"journal-article","created":{"date-parts":[[2024,10,26]],"date-time":"2024-10-26T07:55:28Z","timestamp":1729929328000},"page":"e260966","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Lymphocytic choriomeningitis virus infection following occupational ocular exposure"],"prefix":"10.1136","volume":"17","author":[{"given":"Patricia","family":"Mosset","sequence":"first","affiliation":[{"name":"CHUV, M\u00e9decine du Personnel et d'Entreprise, Lausanne University Hospital, Lausanne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Lazor-Blanchet","sequence":"additional","affiliation":[{"name":"CHUV, M\u00e9decine du Personnel et d'Entreprise, Lausanne University Hospital, Lausanne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2024,10,26]]},"reference":[{"key":"2025082710511681000_17.10.e260966.1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1303.061141"},{"key":"2025082710511681000_17.10.e260966.2","doi-asserted-by":"crossref","DOI":"10.3390\/tropicalmed6020088","article-title":"Lymphocytic Choriomeningitis-Emerging Trends of a Neglected Virus: A Narrative Review","volume":"6","author":"Vilibic-Cavlek","year":"2021","journal-title":"Trop Med Infect Dis"},{"key":"2025082710511681000_17.10.e260966.3","doi-asserted-by":"crossref","DOI":"10.1186\/s13756-019-0524-4","article-title":"Lymphocytic choriomeningitis virus meningitis after needlestick injury: a case report","volume":"8","author":"Dr\u00e4ger","year":"2019","journal-title":"Antimicrob Resist Infect Control"},{"key":"2025082710511681000_17.10.e260966.4","doi-asserted-by":"publisher","DOI":"10.1093\/occmed\/kqv156"},{"key":"2025082710511681000_17.10.e260966.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2011.03.005"},{"key":"2025082710511681000_17.10.e260966.6","doi-asserted-by":"crossref","DOI":"10.1186\/s12985-023-02258-x","article-title":"Armstrong strain lymphocytic choriomeningitis virus infection after accidental laboratory exposure","volume":"20","author":"Caron","year":"2023","journal-title":"Virol J"},{"key":"2025082710511681000_17.10.e260966.7","first-page":"519","article-title":"Contamination de laboratoire avec le virus de la choriom\u00e9ningite lymphocytaire","volume":"61","author":"L\u00e9pine","year":"1938","journal-title":"Ann Inst Pasteur"},{"key":"2025082710511681000_17.10.e260966.8","doi-asserted-by":"crossref","unstructured":"Mosset P , Lazor-Blanchet C , Zurita S , et al . Virus de la choriom\u00e9ningite lymphocytaire (lcmv): cas d\u2019exposition en laboratoire. dans journ\u00e9es franco-suisses de m\u00e9decine et sant\u00e9 au travail, 22-23 juin 2023, Lausanne, Switzerland.","DOI":"10.1016\/j.admp.2023.101914"},{"key":"2025082710511681000_17.10.e260966.9","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa053240"},{"key":"2025082710511681000_17.10.e260966.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jviromet.2011.06.018"},{"key":"2025082710511681000_17.10.e260966.11","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196604282741704"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2024-260966","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T17:51:24Z","timestamp":1756317084000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2024-260966"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":11,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2024,10,26]]},"published-print":{"date-parts":[[2024,10]]}},"alternative-id":["10.1136\/bcr-2024-260966"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2024-260966","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10]]}}}