{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T18:10:04Z","timestamp":1756318204057,"version":"3.44.0"},"reference-count":23,"publisher":"BMJ","issue":"7","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,7,20]]},"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:p>Transverse vaginal septum (TVS) is a rare obstructive genital tract anomaly. It is associated with primary amenorrhoea and typically presents with cyclical abdominal pain due to obstruction of the menstrual flow. Caudal regression syndrome (CRS) is also a rare congenital anomaly that is frequently associated with anomalies of the neurological, musculoskeletal, cardiac, genitourinary and gastrointestinal systems. Obstructive genital tract anomaly in CRS is exceptionally rare. This report describes the case of a girl in early adolescence with underlying CRS who presented with severe abdominal pain associated with primary amenorrhoea. Clinical and radiological assessment revealed \u2018haematocolpos\u2019 manifesting as a tender 20 weeks\u2019 size abdominal mass and an absent vaginal opening. TVS was identified during examination under anaesthesia. The patient subsequently underwent a successful vaginoplasty with no recurrence of symptoms after 2 years.<\/jats:p>","DOI":"10.1136\/bcr-2024-261142","type":"journal-article","created":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T22:40:44Z","timestamp":1722379244000},"page":"e261142","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Caudal regression syndrome associated with obstructive genital tract anomaly"],"prefix":"10.1136","volume":"17","author":[{"given":"Muhammad Hairie Hakimi","family":"Harun","sequence":"first","affiliation":[{"name":"Universiti Sultan Zainal Abidin, Kuala Terengganu, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norul Faqiehah","family":"Mohd Nor","sequence":"additional","affiliation":[{"name":"Hospital Sultanah Nur Zahirah, Kuala Terengganu, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0914-6079","authenticated-orcid":false,"given":"Roziana","family":"Ramli","sequence":"additional","affiliation":[{"name":"Hospital Sultanah Nur Zahirah, Kuala Terengganu, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,7,30]]},"reference":[{"key":"2025082710371741000_17.7.e261142.1","doi-asserted-by":"publisher","DOI":"10.4065\/70.10.965"},{"key":"2025082710371741000_17.7.e261142.2","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-005-1451-4"},{"key":"2025082710371741000_17.7.e261142.3","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1007\/s11604-021-01115-7","article-title":"Congenital anomalies causing hemato\/hydrocolpos: imaging findings, treatments, and outcomes","volume":"39","author":"Tanitame","year":"2021","journal-title":"Jpn J Radiol"},{"key":"2025082710371741000_17.7.e261142.4","unstructured":"Gasner A , Rehman A . 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