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He experienced a single rectal bleeding episode 9 months prediagnosis, with subsequent severe iron-deficiency anaemia and no clear gastrointestinal source identified on gastroscopy. For 2 months, he had intermittent postprandial diarrhoea without abdominal pain, infectious or inflammatory causes. He experienced significant weight loss over 3 months prediagnosis. Subsequent gastroscopy indicated duodenal-gastric food retropulsion, suggesting a downstream blockage. Magnetic resonance enterography showed proximal jejunum thickening. Push enteroscopy confirmed jejunum adenocarcinoma. CT scans detected liver and peritoneal metastases. After one chemotherapy cycle, his condition worsened, leading to his passing 2 months post diagnosis.<\/jats:p>","DOI":"10.1136\/bcr-2024-261407","type":"journal-article","created":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T12:06:23Z","timestamp":1725019583000},"page":"e261407","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Non-specific presentation of metastatic small bowel adenocarcinoma with diagnostic challenges"],"prefix":"10.1136","volume":"17","author":[{"given":"Dora","family":"Chakroun","sequence":"first","affiliation":[{"name":"Medicine, H\u00f4pital du Jura Bernois SA, Saint-Imier, Bern, Switzerland"},{"name":"Medicine, H\u00f4pital du Jura Bernois SA, Saint-Imier, Bern, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathalie","family":"Marnas","sequence":"additional","affiliation":[{"name":"Radiology Institute, H\u00f4pital du Jura Bernois SA, Saint-Imier, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ioannis","family":"Kapoglou","sequence":"additional","affiliation":[{"name":"Gastroenterology, Inselspital Universitatsspital Bern, Bern, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin D","family":"Berger","sequence":"additional","affiliation":[{"name":"Medical Oncology, Inselspital Universitatsspital Bern, Bern, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Wartenberg","sequence":"additional","affiliation":[{"name":"Institute of Tissue Medicine and Pathology, University of Bern, Bern, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uwe","family":"Schiemann","sequence":"additional","affiliation":[{"name":"Medicine, H\u00f4pital du Jura Bernois SA, Saint-Imier, Bern, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,8,30]]},"reference":[{"key":"2025082711304068000_17.8.e261407.1","unstructured":"National Cancer Institute, National Institutes of Health . 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