{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T04:22:34Z","timestamp":1776918154073,"version":"3.51.2"},"reference-count":10,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,12,18]]},"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>A woman in her 50s underwent simple limbal epithelial transplantation (SLET) in the left eye for chemical injury with total limbal stem cell deficiency. A seroma, a hitherto unreported complication of the procedure was noted on the 10th postoperative day. It was associated with an accumulation of inflammatory cells and exudates in the inferior part of the amniotic membrane resembling a hypopyon. After careful exclusion of infectious keratitis on clinical examination, the bandage contact lens was removed and the seroma was drained with a 26G hypodermic needle. A small seroma reappeared over the central cornea 2\u2009weeks later but no donor limbal tissue was seen to be detached from the corneal surface. The patient was managed conservatively. By the third postoperative month, the amniotic membrane disintegrated and the patient achieved an epithelised corneal surface with the relative clearing of the corneal stroma.<\/jats:p>","DOI":"10.1136\/bcr-2024-261530","type":"journal-article","created":{"date-parts":[[2025,1,19]],"date-time":"2025-01-19T20:50:13Z","timestamp":1737319813000},"page":"e261530","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Seroma under the amniotic membrane following simple limbal epithelial transplantation"],"prefix":"10.1136","volume":"18","author":[{"given":"Rishabh","family":"Sah","sequence":"first","affiliation":[{"name":"Cornea, Dr Shroff's Charity Eye Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikunj","family":"Patel","sequence":"additional","affiliation":[{"name":"Cornea, Dr Shroff's Charity Eye Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Virender Singh","family":"Sangwan","sequence":"additional","affiliation":[{"name":"Cornea, Dr Shroff's Charity Eye Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,1,19]]},"reference":[{"key":"2025082711411613000_18.1.e261530.1","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.ajo.2018.01.020","article-title":"Limbal Stem Cell Deficiency-Demography and Underlying Causes","volume":"188","author":"Vazirani","year":"2018","journal-title":"Am J Ophthalmol"},{"key":"2025082711411613000_18.1.e261530.2","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2011-301164"},{"key":"2025082711411613000_18.1.e261530.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2015.12.042"},{"key":"2025082711411613000_18.1.e261530.4","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.4103\/ijo.IJO_632_19","article-title":"Cutting corners, or simplifying technology to reach more patients; using the body as its own incubator for epithelial regeneration","volume":"67","author":"Sangwan","year":"2019","journal-title":"Indian J Ophthalmol"},{"key":"2025082711411613000_18.1.e261530.5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.2006.03949.x"},{"key":"2025082711411613000_18.1.e261530.6","first-page":"483","article-title":"Postmastectomy seromas and wound drainage","volume":"165","author":"Tadych","year":"1987","journal-title":"Surg Gynecol Obstet"},{"key":"2025082711411613000_18.1.e261530.7","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000253445.76991.de"},{"key":"2025082711411613000_18.1.e261530.8","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/s10029-009-0603-1","article-title":"Do drainage liquid characteristics serve as predictors for seroma formation after incisional hernia repair?","volume":"14","author":"Klink","year":"2010","journal-title":"Hernia"},{"key":"2025082711411613000_18.1.e261530.9","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.2217\/fon.13.257","article-title":"Techniques in the Prevention and Management of Seromas After Breast Surgery","volume":"10","author":"H Turner","year":"2014","journal-title":"Future Oncol"},{"key":"2025082711411613000_18.1.e261530.10","doi-asserted-by":"crossref","first-page":"5062","DOI":"10.3390\/jcm11175062","article-title":"Management of Postoperative Seroma: Recommendations Based on a 12-Year Retrospective Study","volume":"11","author":"Papanikolaou","year":"2022","journal-title":"J Clin Med"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2024-261530","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T18:41:22Z","timestamp":1756320082000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2024-261530"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":10,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,1,19]]},"published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1136\/bcr-2024-261530"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2024-261530","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]}}}