{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:47:54Z","timestamp":1787320074505,"version":"build-2736575974"},"reference-count":13,"publisher":"BMJ","issue":"11","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,10,24]]},"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:p>Neuroendocrine tumours of the extrahepatic bile ducts are extremely rare, accounting for only 0.2\u20132% of gastrointestinal tract neuroendocrine neoplasms. Here, we present an incidental finding of this rare tumour, identified during staging scans post-resection of a malignant rectosigmoid polyp and treated with resection and biliary reconstruction. A suspicious, arterially enhancing porta hepatis lymph node was identified on CT and further investigated with liver MRI and 68Ga DOTATATE PET. These revealed a lobulated lesion of the hilum which showed marked avidity without metastases. The patient underwent a successful radical resection of the extrahepatic biliary ducts (including the left, right and common hepatic ducts), the common bile duct and hepaticojejunostomy formation. Histology revealed a 20-mm well-differentiated NET, WHO Grade 2. Two years later, the patient is alive and well without recurrence. This fascinating case illustrates the importance of thorough preoperative planning of surgical resection for tumours at an unusual primary site.<\/jats:p>","DOI":"10.1136\/bcr-2024-261745","type":"journal-article","created":{"date-parts":[[2024,11,11]],"date-time":"2024-11-11T23:40:38Z","timestamp":1731368438000},"page":"e261745","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Primary neuroendocrine tumour of the extrahepatic biliary duct"],"prefix":"10.1136","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5141-0446","authenticated-orcid":false,"given":"Sarah","family":"Fennelly","sequence":"first","affiliation":[{"name":"General Surgery, Northern Hospital Epping, Epping, Victoria, Australia"},{"name":"Master of Cancer Sciences, The University of Melbourne Faculty of Medicine Dentistry and Health Sciences, Melbourne, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Basilie","family":"Teoh","sequence":"additional","affiliation":[{"name":"Hepatobiliary Surgery, Northern Hospital Epping, Epping, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jyothirmayi","family":"Velaga","sequence":"additional","affiliation":[{"name":"Radiology, Northern Hospital Epping, Epping, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nezor","family":"Houli","sequence":"additional","affiliation":[{"name":"Hepatobiliary Surgery, Northern Hospital Epping, Epping, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2024,11,11]]},"reference":[{"key":"2025082707302964000_17.11.e261745.1","doi-asserted-by":"crossref","first-page":"1959","DOI":"10.1002\/(SICI)1097-0142(19991115)86:10<1959::AID-CNCR12>3.0.CO;2-H","article-title":"Carcinoid tumors of the extrahepatic bile duct. A rare cause of malignant biliary obstruction","volume":"86","author":"Chamberlain","year":"1999","journal-title":"Cancer"},{"key":"2025082707302964000_17.11.e261745.2","first-page":"277","article-title":"Carcinoid Tumours (Argentaffinomata): Hunterian Lecture delivered at the Royal College of Surgeons of England on 3rd March 1959","volume":"25","author":"Davies","year":"1959","journal-title":"Ann R Coll Surg Engl"},{"key":"2025082707302964000_17.11.e261745.3","doi-asserted-by":"publisher","DOI":"10.1002\/dc.10098"},{"key":"2025082707302964000_17.11.e261745.4","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.111.101675"},{"key":"2025082707302964000_17.11.e261745.5","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-008-1030-8"},{"key":"2025082707302964000_17.11.e261745.6","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1007\/s13193-022-01621-8","article-title":"Neuroendocrine Tumours of Extrahepatic Biliary Tract: Report of Four Cases with Literature Review","volume":"15","author":"Chopde","year":"2024","journal-title":"Indian J Surg Oncol"},{"key":"2025082707302964000_17.11.e261745.7","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.ijscr.2020.11.027","article-title":"Neuroendocrine tumor of the common bile duct: A case report of extremely rare cause for obstructive jaundice","volume":"77","author":"Miri","year":"2020","journal-title":"Int J Surg Case Rep"},{"key":"2025082707302964000_17.11.e261745.8","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1111\/pin.13317","article-title":"Low-grade mixed neuroendocrine-non-neuroendocrine neoplasm of the extrahepatic bile duct: A rare tumour with 11 years\u2019 follow-up before surgery","volume":"73","author":"Kubota","year":"2023","journal-title":"Pathol Int"},{"key":"2025082707302964000_17.11.e261745.9","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1007\/s12664-012-0197-x","article-title":"Neuroendocrine tumor of common hepatic duct","volume":"31","author":"Bhalla","year":"2012","journal-title":"Indian J Gastroenterol"},{"key":"2025082707302964000_17.11.e261745.10","doi-asserted-by":"crossref","first-page":"099","DOI":"10.1055\/s-0043-1770923","article-title":"Gastrointestinal Subepithelial Lesions: A Review","volume":"14","author":"Pal","year":"2023","journal-title":"J Dig Endosc"},{"key":"2025082707302964000_17.11.e261745.11","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S0039-6060(98)70249-1","article-title":"Aggressive surgical approaches to hilar cholangiocarcinoma: hepatic or local resection?","volume":"123","author":"Miyazaki","year":"1998","journal-title":"Surgery"},{"key":"2025082707302964000_17.11.e261745.12","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1007\/s00268-013-1909-9","article-title":"Liver Resection for Bismuth Type I and Type II Hilar Cholangiocarcinoma","volume":"37","author":"Lim","year":"2013","journal-title":"World j surg"},{"key":"2025082707302964000_17.11.e261745.13","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1007\/s00268-012-1878-4","article-title":"One\u2010stage Resection for Bismuth Type IV Hilar Cholangiocarcinoma with High Hilar Resection and Parenchyma\u2010preserving Strategies: A Cohort Study","volume":"37","author":"Tan","year":"2013","journal-title":"World j surg"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2024-261745","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T14:30:37Z","timestamp":1756305037000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2024-261745"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":13,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2024,11,11]]},"published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1136\/bcr-2024-261745"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2024-261745","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11]]}}}