{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T05:40:06Z","timestamp":1756359606574,"version":"3.44.0"},"reference-count":9,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,12,18]]},"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>Descemet\u2019s membrane (DM) detachment is a significant, if rare, risk of intracameral injection of viscoelastic to treat hypotony after glaucoma filtration surgery. We describe two cases of DM detachment following inadvertent injection of viscoelastic into the posterior stroma and the techniques used for their repair. In both cases, conventional air tamponade failed to resolve the detachment, and further surgical intervention was required. One underwent anterior drainage through venting incisions performed in the operating theatre, while the other had posterior drainage through the DM performed on the slit lamp. Both cases had complete resolution with a good visual outcome and preservation of the glaucoma surgery. Management of this type of detachment requires close coordination between corneal and glaucoma specialists, and the surgical option selected should be tailored to the specific detachment. When managed appropriately, a good visual outcome can be achieved without needing corneal graft surgery and minimising the bleb scarring process.<\/jats:p>","DOI":"10.1136\/bcr-2024-261833","type":"journal-article","created":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T21:10:20Z","timestamp":1736457020000},"page":"e261833","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Repair of Descemet\u2019s membrane detachment following inadvertent intrastromal viscoelastic injection for hypotony: anterior and posterior approaches"],"prefix":"10.1136","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2067-4136","authenticated-orcid":false,"given":"James RC","family":"Miller","sequence":"first","affiliation":[{"name":"Moorfields Eye Hospital, Moorfields Eye Hospital NHS Foundation Trust, London, UK"},{"name":"Department of Ophthalmology, Royal Free London NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emil","family":"Kurniawan","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Royal Free London NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brigid","family":"Ning","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Royal Free London NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,1,9]]},"reference":[{"key":"2025082722172522000_18.1.e261833.1","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.survophthal.2019.12.006","article-title":"Descemet membrane detachment","volume":"65","author":"Singhal","year":"2020","journal-title":"Surv Ophthalmol"},{"key":"2025082722172522000_18.1.e261833.2","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1038\/eye.2017.316","article-title":"Control and optimisation of fluid flow in glaucoma drainage device surgery","volume":"32","author":"Lim","year":"2018","journal-title":"Eye (Lond)"},{"key":"2025082722172522000_18.1.e261833.3","doi-asserted-by":"publisher","DOI":"10.1038\/s41433-021-01595-x"},{"key":"2025082722172522000_18.1.e261833.4","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.ogla.2020.05.001","article-title":"Treatment Outcomes Using the PAUL Glaucoma Implant to Control Intraocular Pressure in Eyes with Refractory Glaucoma","volume":"3","author":"Koh","year":"2020","journal-title":"Ophthalmol Glaucoma"},{"key":"2025082722172522000_18.1.e261833.5","doi-asserted-by":"crossref","first-page":"254","DOI":"10.3129\/i08-018","article-title":"Descemet membrane detachment following viscoelastic injection for posttrabeculectomy hypotony","volume":"43","author":"Rasouli","year":"2008","journal-title":"Can J Ophthalmol"},{"key":"2025082722172522000_18.1.e261833.6","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajoc.2019.100466","article-title":"Descemet\u2019s membrane detachment following an intracameral injection of viscoelastic","volume":"16","author":"Bowden","year":"2019","journal-title":"Am J Ophthalmol Case Rep"},{"key":"2025082722172522000_18.1.e261833.7","doi-asserted-by":"crossref","DOI":"10.1186\/s12886-017-0506-3","article-title":"An alternative technique for Descemet\u2019s membrane detachment following phacoemulsification: case report and review of literature","volume":"17","author":"Weng","year":"2017","journal-title":"BMC Ophthalmol"},{"key":"2025082722172522000_18.1.e261833.8","doi-asserted-by":"crossref","DOI":"10.1186\/s12886-016-0212-6","article-title":"Delayed-onset descemet membrane detachment after uneventful cataract surgery treated by corneal venting incision with air tamponade: a case report","volume":"16","author":"Bhatia","year":"2016","journal-title":"BMC Ophthalmol"},{"key":"2025082722172522000_18.1.e261833.9","doi-asserted-by":"crossref","unstructured":"Singh A , Vanathi M , Sahu S , et al . Intraoperative OCT assisted descemetopexy with stromal vent incisions and intracameral gas injection for case of non-resolving Descemet\u2019s membrane detachment. BMJ Case Rep 2017;2017. doi:10.1136\/bcr-2016-217268","DOI":"10.1136\/bcr-2016-217268"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2024-261833","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T05:17:35Z","timestamp":1756358255000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2024-261833"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":9,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,1,9]]},"published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1136\/bcr-2024-261833"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2024-261833","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2025,1]]}}}