{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T09:40:15Z","timestamp":1756287615892,"version":"3.44.0"},"reference-count":16,"publisher":"BMJ","issue":"11","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,10,25]]},"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:p>Prolonged glucocorticoid overexposure leads to Cushing\u2019s syndrome (CS). It is characterised by diverse metabolic, cardiovascular and bone mineral manifestations. A middle-aged woman presented for a preoperative evaluation of a pathological fracture of the left neck of the femur. She had a history of a hip fracture on the opposite side 3 years back. She exhibited several features specific to CS and was subsequently diagnosed with Cushing\u2019s disease. She underwent transsphenoidal adenoma resection and achieved remission. Glucocorticoids primarily affect the trabecular bone compared with cortical bones, and vertebral fractures are common in CS. The femoral neck consists of both trabecular and cortical bone and can be involved in CS. Our patient was not diagnosed as CS at the first pathological fracture and was subsequently diagnosed only after the second fracture. This case report underscores the importance of a diligent search for a possible endocrinological aetiology in any case of pathological fractures.<\/jats:p>","DOI":"10.1136\/bcr-2024-261896","type":"journal-article","created":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T13:05:14Z","timestamp":1731416714000},"page":"e261896","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Recurrent femoral neck fractures: keep an eye out for Cushing\u2019s syndrome"],"prefix":"10.1136","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-7533-8726","authenticated-orcid":false,"given":"Ahmad","family":"Alam","sequence":"first","affiliation":[{"name":"Endocrinology, Jawaharlal Nehru Medical College and Hospital, Aligarh, Uttar Pradesh, 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