{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T08:57:28Z","timestamp":1767085048342,"version":"3.44.0"},"reference-count":19,"publisher":"BMJ","issue":"3","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,12,2]]},"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:p>Haemophagocytic lymphohistiocytosis (HLH) is a condition of uncontrolled immune activation caused by genetic defects or triggered by infections, malignancies, autoimmune diseases, drugs, pregnancy or post-transplant immunosuppression. This case describes a young man presenting with clinical jaundice and abnormal blood tests, including raised inflammatory markers, abnormal liver function, low haemoglobin (65\u2009g\/L) and a low white blood cell count (3.08\u00d710<jats:sup>9<\/jats:sup>\/L). He met five out of eight HLH criteria and tested positive for Epstein-Barr virus (EBV) PCR (58\u2009011\u2009IU\/mL). His bone marrow biopsy showed EBV-driven Hodgkin\u2019s lymphoma. He was initially treated with the HLH-94 protocol and later switched to ABVD chemotherapy (adriamycin, bleomycin, vinblastine and dacarbazine). He steadily recovered despite a prolonged hospital stay. He was discharged to complete his remaining cycles of chemotherapy as an outpatient with a plan of having a positron emission tomography (PET) scan after two cycles of chemotherapy.<\/jats:p>","DOI":"10.1136\/bcr-2024-261944","type":"journal-article","created":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T09:40:47Z","timestamp":1741945247000},"page":"e261944","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Haemophagocytic lymphohistiocytosis (HLH) with concurrent Hodgkin\u2019s Disease"],"prefix":"10.1136","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-3309-9337","authenticated-orcid":false,"given":"Vanessa","family":"Ambrose Fistus","sequence":"first","affiliation":[{"name":"Acute Medicine, Royal Preston Hospital, Preston, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohiuddin","family":"Sharief","sequence":"additional","affiliation":[{"name":"Acute Internal Medicine, 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