{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,20]],"date-time":"2025-03-20T01:10:19Z","timestamp":1742433019792,"version":"3.40.1"},"reference-count":20,"publisher":"BMJ","issue":"2","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2025,1,16]]},"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:p>Castleman disease is a rare, heterogeneous group of lymphoproliferative disorders whose imaging characteristics can resemble malignancy. We present a case of a patient who initially presented with intermittent hypertension, palpitations, and chest pain. Despite a negative biochemical workup, CT imaging revealed a left retroperitoneal mass intimately associated with the left adrenal gland with 68Ga-DOTATATE positron emission tomography-computed tomography (PET\/CT) detecting uptake in the mass as well as several left para-aortic lymph nodes and bone lesions. Based on the imaging findings, the patient was taken to the operating room for resection of what was presumed to be a metastatic neuroendocrine tumour. However, the diagnosis on histopathological examination was hyaline-vascular Castleman disease. While DOTATATE PET\/CT has high sensitivity and specificity for neuroendocrine tumours (NETs), this case report highlights that non-neuroendocrine pathology may result in DOTATATE uptake, and that Castleman disease should be considered when encountering DOTATATE-positive masses on imaging.<\/jats:p>","DOI":"10.1136\/bcr-2024-261970","type":"journal-article","created":{"date-parts":[[2025,2,4]],"date-time":"2025-02-04T16:05:59Z","timestamp":1738685159000},"page":"e261970","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Castleman disease presenting as DOTATATE-positive retroperitoneal mass"],"prefix":"10.1136","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7161-3451","authenticated-orcid":false,"given":"Stephanie 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