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We present a case of axillary arterial line placement resulting in ischaemic limb injury and amputation, highlighting the need to recognise risk factors.<\/jats:p>\n               <jats:p>A woman in her mid-60s underwent a lobectomy for adenocarcinoma of the lung and suffered postoperative complications resulting from arterial line placement. Despite interventions, she developed progressive ischaemia of her left upper limb, necessitating amputation. This case highlights the risks associated with arterial catheterisation and potential adverse outcomes, offering recommendations for arterial line placement in high-risk patients.<\/jats:p>","DOI":"10.1136\/bcr-2024-261994","type":"journal-article","created":{"date-parts":[[2025,1,14]],"date-time":"2025-01-14T07:00:35Z","timestamp":1736838035000},"page":"e261994","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Rare occurrence of upper-limb ischaemia necessitating transhumeral amputation following axillary arterial line placement"],"prefix":"10.1136","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-8368-7879","authenticated-orcid":false,"given":"Allison Clare","family":"Boland","sequence":"first","affiliation":[{"name":"Wayne State University School of Medicine, Detroit, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Genevieve","family":"Joseph-Mofford","sequence":"additional","affiliation":[{"name":"Wayne State University School of Medicine, Detroit, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cassandra","family":"Pino","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Wayne State University School of Medicine, Detroit, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diane","family":"Levine","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Wayne State University School of Medicine, Detroit, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven D","family":"Tennenberg","sequence":"additional","affiliation":[{"name":"Department of Surgery, Wayne State University School of Medicine, Detroit, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rahul","family":"Vaidya","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Wayne State University School of Medicine, Detroit, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,1,14]]},"reference":[{"key":"2025082709581971000_18.1.e261994.1","doi-asserted-by":"crossref","first-page":"4812","DOI":"10.21037\/jtd.2017.10.166","article-title":"Invasive monitoring of blood pressure: a radiant future for brachial artery as an alternative to radial artery catheterisation?","volume":"9","author":"Lakhal","year":"2017","journal-title":"J Thorac Dis"},{"key":"2025082709581971000_18.1.e261994.2","doi-asserted-by":"crossref","DOI":"10.1186\/s13054-020-02859-w","article-title":"How to measure blood pressure using an arterial catheter: a systematic 5-step approach","volume":"24","author":"Saugel","year":"2020","journal-title":"Crit Care"},{"key":"2025082709581971000_18.1.e261994.3","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1016\/j.jvir.2018.12.735","article-title":"Percutaneous Axillary Artery Access in Complex Endovascular Aortic Repair","volume":"30","author":"Meertens","year":"2019","journal-title":"J Vasc Interv Radiol"},{"key":"2025082709581971000_18.1.e261994.4","doi-asserted-by":"publisher","DOI":"10.1186\/cc1489"},{"key":"2025082709581971000_18.1.e261994.5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.1986.tb02402.x"},{"key":"2025082709581971000_18.1.e261994.6","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/52.1.41"},{"key":"2025082709581971000_18.1.e261994.7","unstructured":"Sam Zarbiv MaMP MD . 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