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Vasoactive intestinal peptide tumour (VIPoma) is a rare tumour with an incidence of 0.05%\u20132%\u2009that typically presents with symptoms related to the release of vasoactive intestinal peptide: flushing, diarrhoea and electrolyte abnormalities like hypokalaemia and hypochlorhydria. Historically, the cardiac valves are unaffected. We present a case where a finding of tricuspid regurgitation and stenosis on echocardiography prompted an expedited workup for malignancy ultimately leading to a diagnosis of VIPoma.<\/jats:p>","DOI":"10.1136\/bcr-2024-262229","type":"journal-article","created":{"date-parts":[[2024,11,7]],"date-time":"2024-11-07T12:10:29Z","timestamp":1730981429000},"page":"e262229","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Carcinoid heart findings in vasoactive intestinal peptide-secreting tumour"],"prefix":"10.1136","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-1080-0080","authenticated-orcid":false,"given":"Mugdha","family":"Joshi","sequence":"first","affiliation":[{"name":"Internal Medicine, Harbor-UCLA Medical Center Department of Internal Medicine, Torrance, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-8626-9405","authenticated-orcid":false,"given":"Daniel","family":"Aldea","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, Harbor-UCLA Medical Center, Torrance, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-6726-2517","authenticated-orcid":false,"given":"Peter","family":"Ngo","sequence":"additional","affiliation":[{"name":"Hematology and Oncology, Harbor-UCLA Medical Center Department of Internal Medicine, Torrance, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-3681-9087","authenticated-orcid":false,"given":"Sonia","family":"Shah","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, Harbor-UCLA Medical Center, Torrance, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,11,7]]},"reference":[{"key":"2025082800292961000_17.11.e262229.1","unstructured":"Sandhu S , Jialal I . ViPoma. PubMed, StatPearls Publishing, 2020. Available: www.ncbi.nlm.nih.gov\/books\/NBK507698\/"},{"key":"2025082800292961000_17.11.e262229.2","unstructured":"Mulla S , et al . Tricuspid Regurgitation. StatPearls, National Library of Medine, 2022. Available: www.ncbi.nlm.nih.gov\/books\/NBK526121\/"},{"key":"2025082800292961000_17.11.e262229.3","doi-asserted-by":"crossref","unstructured":"Arsalan M , Walther T , et al . Tricuspid regurgitation diagnosis and treatment. Eur Heart J 2015. doi:10.1093\/eurheartj\/ehv487","DOI":"10.1093\/eurheartj\/ehv487"},{"key":"2025082800292961000_17.11.e262229.4","unstructured":"Pandit S , et al . Carcinoid Syndrome. StatPearls, National Library of Medine, 2023. Available: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK448096\/"},{"key":"2025082800292961000_17.11.e262229.5","doi-asserted-by":"publisher","DOI":"10.4065\/77.2.139"},{"key":"2025082800292961000_17.11.e262229.6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2016.12.030"},{"key":"2025082800292961000_17.11.e262229.7","unstructured":"deHerder WW , Wouter W , Hofland J . Vasoactive Intestinal Peptide-Secreting Tumor (VIPOMA). PubMed, MDTextcom, Inc, 2000. Available: www.ncbi.nlm.nih.gov\/books\/NBK278960\/"},{"key":"2025082800292961000_17.11.e262229.8","first-page":"110","article-title":"Carcinoid Heart Valve Disease: Transcatheter Pulmonary Valve-In-Valve Implantation in Failing Biological Xenografts","volume":"24","author":"Conradi","year":"2015","journal-title":"J Heart Valve Dis"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2024-262229","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T07:29:39Z","timestamp":1756366179000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2024-262229"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":8,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2024,11,7]]},"published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1136\/bcr-2024-262229"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2024-262229","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2024,11]]}}}