{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T07:36:19Z","timestamp":1792481779652,"version":"4.5.0"},"reference-count":8,"publisher":"BMJ","issue":"11","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,10,18]]},"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:p>Acute phlegmonous esophagitis (APE) is a rare disease caused by bacterial infection of the oesophagus, typically involving the submucosal and muscularis layers. Patients may present with chest pain, dysphagia, odynophagia, dyspnoea, fever, nausea and vomiting, making diagnosis difficult. We present two cases of APE, both young females who presented with dysphagia and odynophagia. The first patient had a history of surgery (left mastoidectomy) which might have functioned as a nidus for infection, whereas the second patient had uncontrolled diabetes. CT findings in both patients revealed diffuse oesophageal thickening, and oesophagogastroduodenoscopy showed erythema and ulcerations. Both patients were managed conservatively using intravenous antibiotics and supportive therapy. APE is associated with a high mortality rate and warrants early diagnosis and treatment. CT is the preferred non-invasive diagnostic modality. Treatment includes systemic antibiotics, nutritional support and timely endoscopic or surgical intervention. Invasive intervention is indicated in patients not responding to medical therapy or in those with complications.<\/jats:p>","DOI":"10.1136\/bcr-2024-262320","type":"journal-article","created":{"date-parts":[[2024,11,9]],"date-time":"2024-11-09T01:30:19Z","timestamp":1731115819000},"page":"e262320","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Acute phlegmonous esophagitis"],"prefix":"10.1136","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6876-9137","authenticated-orcid":false,"given":"Prashant","family":"Gopal","sequence":"first","affiliation":[{"name":"Medical Gastroenterology, Dr D Y Patil Medical College, Hospital and Research Centre, Dr D Y Patil Vidyapeeth (Deemed to be University), Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amol","family":"Dahale","sequence":"additional","affiliation":[{"name":"Medical Gastroenterology, Dr D Y Patil Medical College, Hospital and Research Centre, Dr D Y Patil Vidyapeeth (Deemed to be University), Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aniket","family":"Payagude","sequence":"additional","affiliation":[{"name":"Department of Surgical Gastroenterology, Manipal Hospital, Baner, Pune, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7794-7831","authenticated-orcid":false,"given":"Debabrata","family":"Banerjee","sequence":"additional","affiliation":[{"name":"Medical Gastroenterology, Dr D Y Patil Medical College, Hospital and Research Centre, Dr D Y Patil Vidyapeeth (Deemed to be University), Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2024,11,8]]},"reference":[{"key":"2025082800461421000_17.11.e262320.1","doi-asserted-by":"crossref","unstructured":"Bell D , Worsley C , Deng F , et al . Reference article, radiopaedia.org. Available: https:\/\/doi.org\/10.53347\/rID-71257 [Accessed 11 Jul 2024].","DOI":"10.53347\/rID-71257"},{"key":"2025082800461421000_17.11.e262320.2","doi-asserted-by":"crossref","first-page":"453","DOI":"10.5090\/kjtcs.2017.50.6.453","article-title":"Phlegmonous Esophagitis Treated with Internal Drainage and Feeding Jejunostomy","volume":"50","author":"Woo","year":"2017","journal-title":"Korean J Thorac Cardiovasc Surg"},{"key":"2025082800461421000_17.11.e262320.3","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2010.25.10.1532"},{"key":"2025082800461421000_17.11.e262320.4","doi-asserted-by":"crossref","first-page":"45","DOI":"10.3348\/jksr.2018.79.1.45","article-title":"Acute Phlegmonous Esophagitis with Mediastinitis Complicated by an Esophageal Perforation: A Case Report","volume":"79","author":"Shin","year":"2018","journal-title":"J Korean Soc Radiol"},{"key":"2025082800461421000_17.11.e262320.5","doi-asserted-by":"crossref","DOI":"10.3390\/medicina58070864","article-title":"Usefulness of Contrast-Enhanced CT in a Patient with Acute Phlegmonous Esophagitis: A Case Report and Literature Review","volume":"58","author":"Yun","year":"2022","journal-title":"Medicina (Kaunas)"},{"key":"2025082800461421000_17.11.e262320.6","doi-asserted-by":"crossref","first-page":"262","DOI":"10.4166\/kjg.2022.098","article-title":"Esophageal Stricture after Endoscopic Drainage of Esophageal Abscess as a Complication of Acute Phlegmonous Esophagitis: A Case Report","volume":"80","author":"Kim","year":"2022","journal-title":"Korean J Gastroenterol"},{"key":"2025082800461421000_17.11.e262320.7","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1159\/000521485","article-title":"New Endoscopic Solutions in Managing Phlegmonous Esophagitis","volume":"40","author":"Santos","year":"2022","journal-title":"Dig Dis"},{"key":"2025082800461421000_17.11.e262320.8","doi-asserted-by":"crossref","DOI":"10.3390\/jcm12227147","article-title":"Optimal Management of Patients with Phlegmonous Esophagitis: A Systematic Review and Meta-Analysis","volume":"12","author":"Jin","year":"2023","journal-title":"J Clin Med"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2024-262320","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T07:46:26Z","timestamp":1756367186000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2024-262320"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":8,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2024,11,8]]},"published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1136\/bcr-2024-262320"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2024-262320","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11]]}}}