{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T04:09:09Z","timestamp":1792382949073,"version":"4.4.0"},"reference-count":8,"publisher":"BMJ","issue":"10","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,9,17]]},"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:p>We present a case of a girl in her early childhood with a background of chromosomal deletion 10q21.2, hypothyroidism, second-degree atrioventricular block, developmental delay, gastroesophageal reflux disease, constipation and recurrent fevers. She had subcutaneous nodules, which represented panniculitis. Diagnosis of fever of unknown origin (FUO) associated with panniculitis was very challenging despite the involvement of geneticist, dermatologist, rheumatologist and paediatrician. To detect possible malignant cases and start treatment plans promptly, the case emphasises the need for a comprehensive diagnostic examination, which includes an early biopsy of nodular lesions. To maximise patient outcomes in complicated paediatric presentations, it emphasises the need for continual multidisciplinary teamwork and close monitoring. This case adds to the body of knowledge on the treatment of panniculitis and FUO in paediatric patients, highlighting the need of a comprehensive approach to treatment.<\/jats:p>","DOI":"10.1136\/bcr-2024-262467","type":"journal-article","created":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T10:45:39Z","timestamp":1727779539000},"page":"e262467","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Panniculitis with fever of unknown origin"],"prefix":"10.1136","volume":"17","author":[{"given":"Dhanushan","family":"Gnanendran","sequence":"first","affiliation":[{"name":"Peadiatrics, Scarborough General Hospital, Scarborough, North Yorkshire, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thamir","family":"Alshamari","sequence":"additional","affiliation":[{"name":"Peadiatrics, Scarborough General Hospital, Scarborough, North Yorkshire, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arif","family":"Muhammad","sequence":"additional","affiliation":[{"name":"Peadiatrics, Scarborough General Hospital, Scarborough, North Yorkshire, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirsten","family":"Mack","sequence":"additional","affiliation":[{"name":"Peadiatrics, Scarborough General Hospital, Scarborough, North Yorkshire, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2024,10,1]]},"reference":[{"key":"2025082708055460000_17.10.e262467.1","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-196102000-00001"},{"key":"2025082708055460000_17.10.e262467.2","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1053\/j.semdp.2016.12.004","article-title":"Panniculitis: A summary","volume":"34","author":"Wick","year":"2017","journal-title":"Semin Diagn Pathol"},{"key":"2025082708055460000_17.10.e262467.3","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1097\/00000372-200012000-00009","article-title":"Panniculitis","volume":"22","author":"Cascajo","year":"2000","journal-title":"Am J Dermatopathol"},{"key":"2025082708055460000_17.10.e262467.4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8019.2010.01336.x"},{"key":"2025082708055460000_17.10.e262467.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2008.05.010"},{"key":"2025082708055460000_17.10.e262467.6","doi-asserted-by":"crossref","first-page":"398","DOI":"10.4067\/S0370-41062017000300014","article-title":"Paniculitis como manifestaci\u00f3n de s\u00edndrome febril prolongado en pediatr\u00eda: Caso cl\u00ednico","volume":"88","author":"Puchi Silva","year":"2017","journal-title":"Rev chil pediatr"},{"key":"2025082708055460000_17.10.e262467.7","article-title":"Mesenteric Panniculitis Presenting as Fever of Unknown Etiology in a Patient with History of Abdominal Surgery","volume":"2018","author":"Irwin","year":"2018","journal-title":"Case Rep Gastrointest Med"},{"key":"2025082708055460000_17.10.e262467.8","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2023-254636","article-title":"Mesenteric panniculitis as a possible cause of fever of unknown origin","volume":"16","author":"Lombana","year":"2023","journal-title":"BMJ Case Rep"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2024-262467","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T15:06:05Z","timestamp":1756307165000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2024-262467"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":8,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2024,10,1]]},"published-print":{"date-parts":[[2024,10]]}},"alternative-id":["10.1136\/bcr-2024-262467"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2024-262467","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10]]}}}